Why is "Head-twitch response" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-27 03:13:11
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
The head-twitch response (HTR), also sometimes known as wet dog shakes (WDS) in rats, is a rapid side-to-side head movement that occurs in mice and rats in association with serotonin 5-HT2A receptor activation. Serotonergic psychedelics like lysergic acid diethylamide (LSD) and psilocybin consistently induce the HTR in rodents, whereas non-hallucinogenic serotonin 5-HT2A receptor agonists do not. Because of this, the HTR is widely employed in scientific research as an animal behavioral model of hallucinogen effects and in the discovery of new psychedelic drugs.
Read more on Wikipedia →Related Topics
Trending Topic Today
Search Interest Perspective
-
Study links psilocybin receptor activation to sustained structural brain changes - PsyPost
-
Healing Without the Hallucinations: The Next Generation of Psilocybin Therapy - Neuroscience News
-
Automated detection of the head-twitch response using wavelet scalograms and a deep convolutional neural network - Nature
-
Emiru criticizes Twitch’s response to assault, confirms she is pressing charges - The Express Tribune
-
An undergrad, twitching rodent heads, DOI, and the DEA: 5 Questions for researcher Alyssa Gillies - The Microdose | Substack
-
Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice - PNAS
-
Tolerance and Tachyphylaxis to Head Twitches Induced by the 5-HT2A Agonist 25CN-NBOH in Mice - Frontiers
-
Changing Minds - UC Davis
-
New compound related to psychedelic ibogaine could treat addiction, depression - Medical Xpress
-
Psychedelic drugs to treat psychiatric disorders - EHU
-
Psychedelic-Like Drug Lacking Hallucinogenic Side Effects Identified with New Sensor - Genetic Engineering and Biotechnology News
-
Antidepressant Psychedelics Could Be Separated From Hallucinations, Suggest Crystal Structure Researchers - Technology Networks
-
Fully automated head-twitch detection system for the study of 5-HT2A receptor pharmacology in vivo | Scientific Reports - Nature
-
Intravenous psilocybin induces dose-dependent changes in functional network organization in rat cortex - Nature
-
Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT - Nature
-
Expanding the psychedelic toolkit - Nature
-
The hallucinogenic renaissance: screening for drug abuse potential - Nature
-
Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder | Translational Psychiatry - Nature
-
Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential | Nature Communications - Nature
-
receptor regulate psychosis-related effects and memory deficits - Nature
-
CYB-210010 is long-acting serotonin 5-HT2A receptor agonist - BioWorld News
-
Gilgamesh Pharmaceuticals discovers new 5-HT2A receptor agonists - BioWorld News
-
PA-915 molecule shows long-lasting antidepressant effects without common side effects in mice - Medical Xpress
-
Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo - Journal of Neuroscience
-
Mindset Pharma Presents Poster at Neuroscience 2022 Highlighting Preclinical Data on MSP-1014, its Psilocybin-like Lead Drug Candidate - Investing News Network
-
Psychedelic mushroom extract may offer enhanced brain benefits over synthetic psilocybin - PsyPost
-
Psychedelic substance 5-MeO-DMT induces long-lasting neural plasticity in mice - PsyPost
-
Fast-acting psychedelic 5-MeO-DMT increases structural neural plasticity in mice, study finds - PsyPost
-
Behavioral Evidence for Interactions between a Hallucinogenic Drug and Group II Metabotropic Glutamate Receptors - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.