Why is "Hematopoietic stem cell" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-04-01 09:46:11
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the (midgestational) aorta-gonad-mesonephros region, through a process known as endothelial-to-hematopoietic transition. In adults, haematopoiesis occurs in the red bone marrow, in the core of most bones. The red bone marrow is derived from the layer of the embryo called the mesoderm. Recent study marks the first global discovery of hematopoietic stem cell (HSC) niches within invertebrate skeletons—overturning the long-held belief that skeletal hematopoiesis is unique to vertebrates.
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Trending Topic Today
Search Interest Perspective
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Non-necroptotic MLKL function damages mitochondria and promotes hematopoietic stem cell aging - Nature
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Hematopoietic Stem-Cell Transplantation - NEJM
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Mechanometabolism instructs hematopoietic stem cell specification - Rockefeller University Press
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Gpr171 regulates embryonic hematopoietic stem cell emergence via ERK1/2 and Notch signaling - PNAS
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Honoring a Pioneer in Hematopoietic Stem Cell Transplantation - ashpublications.org
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Outcomes of hematopoietic stem cell transplantation in patients aged 70 years and older - Nature
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Evaluation of Initial Weight-Based Tacrolimus Dosing After Allogeneic Hematopoietic Stem Cell Transplant - Journal of Hematology Oncology Pharmacy
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Editorial: Advancements in hematopoietic stem cell proliferation and self-renewal maintenance - Frontiers
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Hematopoietic Stem-Cell Gene Therapy for Cystinosis - NEJM
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An extraction pipeline for analysis of hematopoietic stem cell transplantation data - Nature
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A 62-Year-Old Woman with Diarrhea after Hematopoietic Stem-Cell Transplantation - NEJM Evidence
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Shear stress governs hematopoietic stem cell fate to promote inflammation-induced aging - Nature
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A multi-center clinical trial of allogeneic hematopoietic stem cell transplantation in transfusion-dependent thalassemia - Nature
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MAFB regulates hematopoietic stem cell proliferation and maintenance - Nature
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Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity - Nature
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P-selectin overexpression impairs hematopoietic stem cell homeostasis via inflammatory receptor-mediated proliferation and differentiation - Nature
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Suppression of Rho-associated kinase 1 (ROCK1) promotes human hematopoietic stem cell expansion by attenuating mitochondrial fission - Nature
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Human cancer-targeted immunity via transgenic hematopoietic stem cell progeny - Nature
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Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation - Nature
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Machine learning-based prediction of G-CSF-induced hematopoietic stem cell mobilization outcomes in healthy volunteers | Bone Marrow Transplantation - Nature
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Next generation targeted non-genotoxic conditioning for hematopoietic stem cell and hematopoietic stem cell-based gene therapy - Frontiers
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Widespread presence of bone marrow–like hematopoietic stem cell niche in invertebrate skeletons - Science | AAAS
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FDA Approves Narsoplimab for Hematopoietic Stem Cell Transplant–Associated Thrombotic Microangiopathy - OncLive
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Predicting the response to hematopoietic stem cell transplantation in persons with multiple sclerosis: the significance of an early positive response - Nature
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Unlocking hematopoietic stem cell potential: integrative computational approaches for genomic and transcriptomic analysis - Frontiers
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Partial match parity: Increasing the donor pool for hematopoietic stem cell transplantation - Medical Xpress
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Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice - Nature
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Hematopoietic stem cell size heterogeneity is not linked to changes in stem cell potential of aged HSCs - Frontiers
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Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool - Nature
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Haematopoietic stem cell number is not solely defined by niche availability - Nature
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Assessment of thyroid dysfunction as a late complication after hematopoietic stem cell transplantation in pediatric patients | Urbańska | Acta Haematologica Polonica - Via Medica Journals
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Annual bone marrow transplantation workshop explores hematopoietic stem cell transplantation - Stanford Medicine
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Tony Marchand: Excited to Announce our Article on Hematopoietic Stem Cell Regulation - Oncodaily
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High-fat diets promote hematopoietic stem cell expansion and exercise reduces myeloid skewing during maintenance hematopoiesis - American Physiological Society Journal
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Research identifies seven genes that drive hematopoietic stem cell fate - News-Medical
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Pilot nursing study explores physical activity during and after hematopoietic stem cell transplantation - UT MD Anderson
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Continuous map of early hematopoietic stem cell differentiation across human lifetime - Nature
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Hematopoietic stem cell fate under the influence of Ser/Thr protein phosphatases - Haematologica
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Hematopoietic Stem Cell Factors: Their Functional Role in Self-Renewal and Clinical Aspects - Frontiers
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Regulation of the hematopoietic stem cell pool by C-Kit–associated trogocytosis - Science | AAAS
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The aging hematopoietic stem cell niche: a mini review - Frontiers
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Cellular plasticity of the bone marrow niche promotes hematopoietic stem cell regeneration - Nature
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Hematopoietic Stem Cell Transplantation for Neurological Disorders: A Focus on Inborn Errors of Metabolism - Frontiers
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Epigenetic reversal of hematopoietic stem cell aging in Phf6 -knockout mice - Nature
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A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia - Nature
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Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets - Nature
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Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics - Nature
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Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy - NEJM
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Hematopoietic stem cell niche maintenance during homeostasis and regeneration - Nature
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Hematopoietic Stem-Cell Transplantation and Drug Considerations in Transgender Patients - Journal of Hematology Oncology Pharmacy
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Therapeutic efficacy of intracerebral hematopoietic stem cell gene therapy in an Alzheimer’s disease mouse model - Nature
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Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size - Nature
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Reconstructing skeletal homeostasis through allogeneic hematopoietic stem cell transplantation in myelofibrosis - Nature
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-dependent metabolic checkpoint regulates hematopoietic stem cell activation and aging - Nature
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Deregulated protein homeostasis constrains fetal hematopoietic stem cell pool expansion in Fanconi anemia - Nature
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Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate - Nature
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Lipoprotein metabolism mediates hematopoietic stem cell responses under acute anemic conditions - Nature
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Extracellular Vesicles and Hematopoietic Stem Cell Aging - American Heart Association Journals
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Understanding intrinsic hematopoietic stem cell aging - Haematologica
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Hematopoietic Stem-Cell Transplantation - NEJM
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Dynamic biological characteristics of human bone marrow hematopoietic stem cell senescence - Nature
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Genetic fingerprint defines hematopoietic stem cell pool size and function - Haematologica
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A system-level model reveals that transcriptional stochasticity is required for hematopoietic stem cell differentiation - Nature
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Implications of stress-induced gene expression for hematopoietic stem cell aging studies - Nature
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Age-related decline in LEPR+ hematopoietic stem cell function - Leukemia - Nature
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Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells - Nature
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Trim47 prevents hematopoietic stem cell exhaustion during stress by regulating MAVS-mediated innate immune pathway - Nature
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Sleep exerts lasting effects on hematopoietic stem cell function and diversity | Journal of Experimental Medicine - Rockefeller University Press
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Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment - Rockefeller University Press
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The comprehensive DNA methylation landscape of hematopoietic stem cell development - Nature
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Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells - PNAS
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Cardiovascular Management of Patients Undergoing Hematopoietic Stem Cell Transplantation: From Pretransplantation to Survivorship - professional.heart.org
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CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment - Rockefeller University Press
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Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life - Nature
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Hemostasis and complement in allogeneic hematopoietic stem cell transplantation: clinical significance of two interactive systems - Nature
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Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection - Rockefeller University Press
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Hematopoietic stem cell transplantation in inborn errors of metabolism—a retrospective analysis on behalf of the pediatric disease working party from the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy - Nature
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EVA1A regulates hematopoietic stem cell regeneration via ER-mitochondria mediated apoptosis - Nature
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PDK1 plays a vital role on hematopoietic stem cell function - Nature
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Trajectories of quality of life during hematopoietic stem cell transplantation: longitudinal cohort study - Nature
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PTPσ inhibitors promote hematopoietic stem cell regeneration - Nature
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Sex-dependent differences in hematopoietic stem cell aging and leukemogenic potential - Nature
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Deciphering hematopoietic stem cell development: key signaling pathways and mechanisms - Frontiers
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Hematopoietic Stem Cell Niche During Homeostasis, Malignancy, and Bone Marrow Transplantation - Frontiers
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USP4 regulates ribosome biogenesis and protein synthesis for hematopoietic stem cell regeneration and leukemia progression - Nature
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New transgenic mouse models enabling pan-hematopoietic or selective hematopoietic stem cell depletion in vivo - Nature
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Hematopoietic stem cell transplantation for blood cancers in the era of precision medicine and immunotherapy - Wiley
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Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance - Science | AAAS
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Hematopoietic Stem Cell Transplantation Shown to Benefit MS Prognoses - The American Journal of Managed Care® (AJMC®)
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Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1 - Nature
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CCR2 cooperativity promotes hematopoietic stem cell homing to the bone marrow - Science | AAAS
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Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation - Nature
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Cardiac complications associated with hematopoietic stem-cell transplantation - Nature
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Hematopoietic stem cell transplantation-associated thrombotic microangiopathy and the role of advanced practice providers and pharmacists - Nature
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Regulation of Hematopoietic Stem Cell Activity by Inflammation - Frontiers
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Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation - Science | AAAS
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Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche - Nature
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HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the U.S. Registry - NEJM
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Abdominal Complications Following Hematopoietic Stem Cell TransplantationRadioGraphics - RSNA Journals
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Team achieves successful reproduction of hematopoietic stem cell developmental process in an in vitro culture system - Phys.org
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.