Why is "Hepatotoxicity" trending?

Search Interest Perspective

• Multi-lineage hepatic organoids reveal toxic exosome mediated indirect hepatotoxicity - Nature
• Neuronal injury and hepatotoxicity: astrocytes and stellate cells convergence and their role in tissue repair - Frontiers
• Ciprofloxacin-Induced Guillain-Barré Syndrome, Posterior Reversible Encephalopathy Syndrome, Hepatotoxicity, and Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Case Report - Cureus
• Cyanidin-3-O-Glucoside Mitigates Hepatotoxicity Induced by 2-Amino-3-Methylimidazo[4,5-f]Quinoline via Endogenous and Exogenous Apoptotic Signaling Pathways: Evidence From In Vivo and In Silico Studies - Wiley Online Library
• Voriconazole-induced liver injury: incidence patterns and risk factors in a retrospective cohort - ASM Journals
• Hepatotoxicity and Drug-induced Liver Injury (DILI) | Cyprotex - Evotec
• Drug-related hepatotoxicity risk in elderly patients with atrial fibrillation: insights from the nationwide Italian START registry - Nature
• Nivolumab-Associated Acute Liver Failure: A Report of Two Cases - Cureus
• Pharmacogenomic analysis of alarelin acetate-induced hepatotoxicity: a case report and literature review - Frontiers
• Iron overload in CD11c+ myeloid cells exacerbates acetaminophen hepatotoxicity | Communications Biology - Nature
• Silent Threats to the Liver: Acute Hepatotoxicity Attributed to Selective Androgen Receptor Modulators (SARMs) - Cureus
• Treatment experience in managing severe immune-mediated hepatotoxicity induced by immune checkpoint inhibitors - Frontiers
• Targeted cellular depletion in an immune-liver-on-a-chip platform elucidates cell-type-specific heterogeneity in drug-induced hepatotoxicity - Nature
• Late-Onset Immune-Mediated Hepatotoxicity Induced by the Immune Checkpoint Inhibitor Pembrolizumab in Lung Cancer: A Case Report - Cureus
• Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip - Nature
• Double Jeopardy: Lamotrigine-Induced Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Complicated by Valproate Hepatotoxicity - Cureus
• Ameliorative effect of folic acid and vitamin B12 against Ivermectin-induced hepatotoxicity, renal toxicity, oxidative stress and immunohistochemical changes in male albino rats - Nature
• Hepatoprotective potential of M3F, a benzimidazole pyrazole derivative, against paracetamol induced hepatotoxicity - Nature
• Protective effects of melatonin and naringenin against acitretin induced hepatotoxicity via modulation of oxidative stress and inflammatory signaling - Nature
• Real-world pharmacovigilance assessment of hepatotoxicity risk with HER2-Targeted drugs using FAERS database analysis | Scientific Reports - Nature
• Isoliquiritigenin, Nrf2 Activator, and NLRP3 Inhibitor Protects Isoniazid-Induced Hepatotoxicity in Sprague-Dawley Rats: Studies on Oxidative Stress, Inflammation, DNA Damage, Ferroptosis, and Steatosis - Wiley Online Library
• Antioxidant and Hepatotoxicity Ameliorative Potential of Mentha canadensis Leaves Against Paracetamol-Induced Hepatic Damage in Mice - Wiley Online Library
• Inflammasome activation as a key driver of acetaminophen-induced hepatotoxicity: Mechanisms and emerging therapeutics - EurekAlert!
• Therapeutic potential of plant-derived natural products against drug-induced liver injury - Frontiers
• Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in gentamicin-induced hepatotoxicity and nephrotoxicity in rats - Nature
• Microperfused Biomimetic Liver‐on‐a‐Chip for High‐Throughput Hepatotoxicity Screening - Zhao - 2025 - Small - Wiley Online Library
• Idiosyncratic Warfarin-Induced Hepatocellular Injury: A Reversible and Uncommon Occurrence - Cureus
• Protective structural and enzymatic roles of catechin and gallic acid against nephrotoxicity and hepatotoxicity ınduced by cisplatin - Nature
• Network toxicology and molecular docking elucidate the hepatotoxic and carcinogenic mechanisms of potassium sorbate validated by in vitro assays - Nature
• Uncovering mechanism of hepatotoxicity diseases caused by tetrahydrocannabinol based on novel network toxicology and experimental verification - Nature
• Gypenoside XLIX Alleviates Diclofenac-Induced Hepatotoxicity via Modulating Akt/NLRP3 Pathway - Wiley Online Library
• Elevated Hepatotoxicity Risk Linked to Cabozantinib in Cancer Treatment - Physician's Weekly
• Tuberculous Meningitis in a One-Year-Old Child With Isoniazid-Induced Hepatotoxicity: A Case Report - Cureus
• Drug-Induced Liver Injury Secondary to Turmeric Supplement Containing Piperine: A Case Report - Cureus
• Unveiling the Unexpected: A Case of Synergistic Drug Reaction to Cannabidiol - Cureus
• Unveiling the crosstalk between unfolded protein response and apoptosis in triclosan induced hepatotoxicity in Labeo rohita - Nature
• Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling - Nature
• Enterohepatic circulation-inspired nano-platform for less-hepatotoxicity hepatocellular carcinoma therapy - ScienceDirect.com
• Drug-induced liver injury. Part II: Late complications and hepatotoxicity monitoring - Termedia
• From Cholesterol Control to Critical Illness: A Case of Statin-Associated Rhabdomyolysis With Concurrent Acute Kidney Injury and Hepatotoxicity - Cureus
• 'Natural' Isn’t Always Safe: Reframing Herbal-Induced Liver Injury - Medscape
• FDA Wants Drug Pulled From Market, Citing Liver Risk. Company Says No. - MedPage Today
• Drug-Induced Liver Injury Secondary to Meropenem: Diagnostic Challenge and Therapeutic Role of Hemoadsorption - Cureus
• Case Report: Fatal presumptive idiosyncratic hepatic necrosis secondary to standard-dose leflunomide administration in a dog - Frontiers
• Hepatotoxicity evaluation method through multiple-factor analysis using human pluripotent stem cell derived hepatic organoids - Nature
• Predictors of severe hepatotoxicity among retroviral infected adults on HAART regimen in Ilubabor Zone, Southwest Ethiopia - Nature
• 6 supplements, including green tea, turmeric, linked to liver toxicity - Medical News Today
• Drug-Induced Hepatotoxicity - NEJM
• Drug-Induced Cholestasis Secondary to Meropenem in an Elderly Patient: Report of A Rare Case - Cureus
• Mitigating doxorubicin-induced hepatotoxicity in male rats: The role of aerobic interval training and curcumin supplementation in reducing oxidative stress, endoplasmic reticulum stress and apoptosis - Nature
• A virtual scalable model of the Hepatic Lobule for acetaminophen hepatotoxicity prediction - Nature
• Hepatotoxicity to Risperidone - Psychiatrist.com
• From Therapy to Toxicity: A Rare Case of Acute Piperacillin/Tazobactam-Associated Drug-Induced Liver Injury - Cureus
• Busting the myth of methotrexate chronic hepatotoxicity - Nature
• Antidepressant-Induced Liver Injury: A Review for Clinicians - Psychiatry Online
• Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps - Frontiers
• Hepatotoxicity-Related Adverse Effects of Proton Pump Inhibitors: A Cross-Sectional Study of Signal Mining and Analysis of the FDA Adverse Event Report System Database - Frontiers
• Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system - Frontiers
• -induced oxidative stress and hepatotoxicity by Ganoderma lucidum in Long Evans rats - Nature
• The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics - Frontiers
• Risk of potential hepatotoxicity from pirfenidone or nintedanib in patients with idiopathic pulmonary fibrosis: results of a retrospective analysis of a large insurance database in Taiwan - Frontiers
• Protective effect of magnetic water against AlCl3-induced hepatotoxicity in rats | Scientific Reports - Nature
• Contamination of Aflatoxins Induces Severe Hepatotoxicity Through Multiple Mechanisms - Frontiers
• Evaluation of liver function tests to identify hepatotoxicity among acute lymphoblastic leukemia patients who are receiving chemotherapy induction - Nature
• A Rare Case of Methyldopa-Induced Hepatitis - Cureus
• Methotrexate induced hepatotoxicity in metabolic dysfunction-associated steatotic liver disease - Wiley Online Library
• Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities - Nature
• Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity - Nature
• Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives - Frontiers
• Ribociclib-induced liver injury: a case report - Frontiers
• Carbene reactive metabolite explains the hepatotoxicity of the hot flashes drug fezolinetant: A DFT investigation - ScienceDirect.com
• Isoliquiritigenin induced hepatotoxicity and endoplasmic reticulum stress in zebrafish embryos - Nature
• Sodium aescinate-induced hepatotoxicity via ATF4/GSH/GPX4 axis-mediated ferroptosis - Nature
• Discovery of Ketal-Ester Ionizable Lipid Nanoparticle with Reduced Hepatotoxicity, Enhanced Spleen Tropism for mRNA Vaccine Delivery - Wiley
• Proton pump inhibitors reduce chemotherapeutic hepatotoxicity and enhance hepatic uptake and accumulation of drug-loaded extracellular vesicles - Nature
• Association of NAT2 promoter hypermethylation with susceptibility to hepatotoxicity due to antituberculosis drugs and biomarker potential - Nature
• Inflammation aggravated the hepatotoxicity of triptolide by oxidative stress, lipid metabolism disorder, autophagy, and apoptosis in zebrafish - Frontiers
• The molecular pathogenesis of triptolide-induced hepatotoxicity - Frontiers
• High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity - Nature
• Research on the Species Difference of the Hepatotoxicity of Medicine Based on Transcriptome - Frontiers
• Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking - Nature
• A popular hair growth supplement linked to liver failure - MDLinx
• Voxel-Based Dosimetry Predicts Hepatotoxicity in Hepatocellular Carcinoma Patients Undergoing Radioembolization with 90Y Glass Microspheres - Journal of Nuclear Medicine
• Hydroxychloroquine-Induced Hepatotoxicity in Systemic Lupus Erythematous: A Case Report and Literature Review - Cureus
• Severe Hepatotoxicity From Capmatinib: A Case Report and Therapeutic Approach - Cureus
• Evaluation of the hepatotoxicity of Psoralea corylifolia L. based on a zebrafish model - Frontiers
• Even low doses of CBD may cause harm to the liver in some people, FDA study finds - NBC News
• Oveporexton Shows Superior Efficacy in Phase II Narcolepsy Type 1 Trial Without Hepatotoxicity - Applied Clinical Trials Online
• Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal - Frontiers
• Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides - Nature
• DNA polymerase gamma variants and hepatotoxicity during maintenance therapy of childhood acute lymphoblastic leukemia: is there a causal relationship? - Nature
• Macrophage malfunction in Triptolide-induced indirect hepatotoxicity - Frontiers
• Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy - Nature
• Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice - Nature
• New molecular and biochemical insights of doxorubicin-induced hepatotoxicity - ScienceDirect.com
• An investigation of broad-spectrum antibiotic-induced liver injury based on the FDA Adverse Event Reporting System and retrospective observational study - Nature
• Early detection of doxorubicin-induced hepatotoxicity by imaging mitochondrial membrane potential - Journal of Nuclear Medicine
• Anti-tumor effect and hepatotoxicity mechanisms of psoralen - Frontiers
• Drug-Related Hepatotoxicity - NEJM
• Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health - Nature