Why is "Histone modification" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-30 20:23:15
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
In biology, histones are highly-basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei and in most Archaeal phyla. They act as spools around which DNA winds to create structural units called nucleosomes. Nucleosomes in turn are wrapped into 30-nanometer fibers that form tightly packed chromatin. Histones prevent DNA from becoming tangled and protect it from DNA damage. In addition, histones play important roles in gene regulation and DNA replication. Without histones, unwound DNA in chromosomes would be very long. For example, each human cell has about 1.8 meters of DNA if completely stretched out; however, when wound about histones, this length is reduced to about 9 micrometers (0.009 mm) of 30 nm diameter chromatin fibers.
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Trending Topic Today
Search Interest Perspective
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Histone modification changes upon exposure of human lung adenocarcinoma cells to nanoparticles - Nature
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Analysis of histone modification interplay reveals two distinct domains in facultative heterochromatin in Pyricularia oryzae - Nature
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Histone modification–driven structural remodeling unleashes DNMT3B in DNA methylation - Science | AAAS
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Histone modification levels are predictive for gene expression - PNAS
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Histone modification: Biomarkers and potential therapies in colorectal cancer - An - 2023 - Annals of Human Genetics - Wiley Online Library
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Histone Modification Landscapes as a Roadmap for Malaria Parasite Development - Frontiers
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Molecular basis of hUHRF1 allosteric activation for synergistic histone modification binding by PI5P - Science | AAAS
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Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1 - Nature
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Impact of air pollution exposure on cytokines and histone modification profiles at single-cell levels during pregnancy - Science | AAAS
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Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification - Nature
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Linking DNA methylation and histone modification: patterns and paradigms - Nature
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Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array - Nature
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Epigenetic mechanisms of Immune remodeling in sepsis: targeting histone modification - Nature
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An assessment of histone-modification antibody quality - Nature
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TACIT and CoTACIT for histone modification profiling in single cells and lineage tracing - Nature
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Genetic variants in histone modification regions are associated with the prognosis of lung adenocarcinoma - Nature
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Genetically encoded system to track histone modification in vivo - Nature
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Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis - Nature
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Chromatin conformation and histone modification profiling across human kidney anatomic regions - Nature
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Streamlined quantitative analysis of histone modification abundance at nucleosome-scale resolution with siQ-ChIP version 2.0 - Nature
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Allelic reprogramming of the histone modification H3K4me3 in early mammalian development - Nature
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Histone modification important for correct blood cell formation, finds study - Phys.org
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Histone modifications for human epigenome analysis - Nature
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Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome - Nature
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Synergetic effects of DNA methylation and histone modification during mouse induced pluripotent stem cell generation - Nature
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New histone modification identified - C&EN
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Regulation of stomatal opening and histone modification by photoperiod in Arabidopsis thaliana - Nature
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Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry - Nature
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Regulation of histone modification and chromatin structure by the p53–PADI4 pathway - Nature
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Analysis of Müller glia specific genes and their histone modification using Hes1-promoter driven EGFP expressing mouse - Nature
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The LDL1/2-HDA6 Histone Modification Complex Interacts With TOC1 and Regulates the Core Circadian Clock Components in Arabidopsis - Frontiers
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Cancer epigenomics: DNA methylomes and histone-modification maps - Nature
Why This Topic Is Trending
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Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.