Why is "Klinefelter syndrome" trending?
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- Date: 2026-03-17 17:03:51
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Wikipedia Overview
Klinefelter syndrome (KS), also known as 47,XXY, is a chromosome anomaly. Subjects affected by the condition are almost always phenotypically male, with common complications such as infertility and small, poorly functioning testicles. These symptoms are often noticed only at puberty, although this is one of the most common chromosomal disorders. The birth prevalence of KS in the State of Victoria, Australia was estimated to be 223 per 100,000 males. It is named after American endocrinologist Harry Klinefelter, who identified the condition in the 1940s, along with his colleagues at Massachusetts General Hospital.
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Search Interest Perspective
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Sperm Retrieval for Patients With Klinefelter Syndrome - Cleveland Clinic
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Underrecognized Thrombotic Risk in Klinefelter Syndrome: A Clinical Insight - Cureus
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Case Report: Diabetic ketoacidosis in a patient with Klinefelter syndrome: a rare and complex presentation - Frontiers
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New insights needed to improve fertility outcomes in patients with Klinefelter syndrome - Urology Times
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Age and Sperm Retrieval Outcomes in Klinefelter Syndrome - European Medical Journal
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Perspectives From Adolescents and Young Adults With Klinefelter Syndrome on Testosterone Supplementation and Fertility - Endocrine Society
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Late Diagnosis of Klinefelter Syndrome: Overcoming Phenotypic Variability and Diagnostic Oversights - Wiley Online Library
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Mom 'Terrified' After Test Reveals Son Has XXY Chromosome (Exclusive) - People.com
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The most common genetic variation you’ve probably never heard of… - British Psychological Society
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What factors influence sperm retrieval success in patients with Klinefelter syndrome? - Urology Times
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Testosterone Levels Predict Sperm Retrieval in Klinefelter Syndrome - European Medical Journal
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X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome - Nature
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Klinefelter syndrome: many men have an extra X chromosome – but it is rarely diagnosed - The Guardian
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Schizophrenia in Klinefelter Syndrome - Psychiatrist.com
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Prevalence and Application of Speech-Language Therapy in Individuals With Klinefelter Syndrome: A Scoping Review - Cureus
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Does age affect sperm retrieval in patients with Klinefelter Syndrome? - Urology Times
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Editorial: Fertility in Klinefelter Syndrome: The Need for a Multidisciplinary Approach - Frontiers
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Concurrent Diagnosis and Management of Primary Mediastinal Germ Cell Tumor and Klinefelter Syndrome - Cureus
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Leila Momtazi-Mar discusses sperm retrieval in patients with Klinefelter Syndrome - Urology Times
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Unveiling Psychiatric Complexities in 48,XXYY Syndrome: A Case Study - Cureus
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Man born with an extra chromosome reveals main symptom to look for - UNILAD Tech
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How Successful Is Surgical Sperm Retrieval in Klinefelter Syndrome? - Frontiers
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Expression profile of microRNAs in the testes of patients with Klinefelter syndrome - Nature
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Achalasia in Klinefelter syndrome: A suspected pediatric case as well as prevalence analysis suggesting increased risk in this population - Wiley Online Library
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New insights into Klinefelter syndrome and male infertility - News-Medical
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High Risk of Venous Thromboembolism in Klinefelter Syndrome - American Heart Association Journals
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Klinefelter Syndrome Diagnosis Masked by Opioid Use Disorder - Cureus
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The Evidence for Fertility Preservation in Pediatric Klinefelter Syndrome - Frontiers
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Quality of life in men with Klinefelter syndrome: the impact of genotype, health, socioeconomics, and sexual function - Nature
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Rare Double Aneuploidy (Down-Klinefelter Syndrome): A Case Report - Cureus
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Indeterminate Lesions of the Testis in Klinefelter Syndrome—Should We Be Concerned? - Frontiers
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Veterans Help Provide Greater Insight into Klinefelter and Jacobs Syndromes - CU Anschutz newsroom
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Decreased miRNA expression in Klinefelter syndrome - Nature
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DNA hypermethylation and differential gene expression associated with Klinefelter syndrome - Nature
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Klinefelter Syndrome Presenting as Suicidal Attempt - Cureus
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Case report: Klinefelter syndrome may protect against the development of spinal and bulbar muscular atrophy - Frontiers
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Is the prevalence of Klinefelter syndrome increasing? - Nature
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Man diagnosed with extra chromosome at 31 reveals first sexual side effects which indicated something wasn't right - UNILAD
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Pacific Center for Sex and Society - Androgen Insensitivity Syndrome and Klinefelter's Syndrome - University of Hawaii System
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Down-Klinefelter Syndrome With Concurrent Double Aneuploidy in an Indian Child - Cureus
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Why I Empathize With Trump (And a Lesson on Sex) - Spectrum Magazine
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Venous thromboembolism in Klinefelter syndrome: a clot in the knowledge? - Wiley Online Library
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A child with Klinefelter syndrome and both IgE-mediated food allergy and low proportion of naive Treg - Wiley Online Library
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First-of-its-kind stem cell study sheds light on Klinefelter syndrome - Medical Xpress
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Transcriptomic differences between fibrotic and non-fibrotic testicular tissue reveal possible key players in Klinefelter syndrome-related testicular fibrosis - Nature
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Bilateral Testicular Epidermoid Cysts in a Man with Klinefelter Syndrome: A Case Report - Cureus
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Pulmonary embolism in a patient with Klinefelter's syndrome - Tidsskrift for Den norske legeforening
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Neuroanatomical Phenotype of Klinefelter Syndrome in Childhood: A Voxel-Based Morphometry Study - Journal of Neuroscience
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Early detection linked to improved quality of life in boys with Klinefelter Syndrome - Emory University
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Human genetic disease - Sex Chromosome Abnormalities - Britannica
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Simple treatment can save lives for men with a common chromosomal disorder - Medical Xpress
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Testicular blood supply is altered in the 41,XXY* Klinefelter syndrome mouse model | Scientific Reports - Nature
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Oldest Case of Klinefelter Syndrome Diagnosed in Ancient Skeleton - Technology Networks
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Sleep Issues Common in Children With Klinefelter Syndrome - Medscape
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Klinefelter's syndrome changes cancer risk - The Lancet
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Klinefelter's Syndrome in a Ten-Month-Old Mongolian Idiot — Report of a Case with Chromosome Analysis - NEJM
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Integrated Care Approach Benefits Patients with Klinefelter Syndrome | Newswise - Newswise
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Concurrence of Klinefelter Syndrome With Hypospadias and Chordee in Identical Twins: A Rare Presentation - ScienceDirect.com
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Bone mineralization and immediate function of six dental implants in patients with Klinefelter syndrome - Wiley Online Library
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Klinefelter syndrome: a general practice perspective - Royal Australian College of General Practitioners (RACGP)
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Testicular Size in Klinefelter's Syndrome in Men over Fifty — Report of a Case with XXY/XY Mosaicism - NEJM
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Developing a New Tool to Detect a Frequently Missed Sex Chromosome Disorder in Boys - Columbia University Irving Medical Center
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Testicular microvascular flow is altered in Klinefelter syndrome and predicts circulating testosterone - medRxiv
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Prostate Cancer, Gender Identity, and Testosterone Replacement Therapy in Klinefelter Syndrome: A Case Report and Literature Review - Cureus
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Understanding the genetic factors that drive Klinefelter syndrome and related diseases - Medical Xpress
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New hope for male infertility: Researchers discover key mechanism in Klinefelter syndrome - Medical Xpress
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Magdalen College - individual with Klinefelter syndrome (IMAGE) - EurekAlert!
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Successful treatment of a patient with Klinefelter's syndrome complicated by mediastinal germ cell tumor and AML(M7) - Nature
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Oldest case of a rare genetic condition discovered - EurekAlert!
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Three cases of Klinefelter's syndrome with unilateral absence of vas deferens - Akinsal - 2017 - Andrologia - Wiley Online Library
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Rare Genetic Syndrome in 1,000-Year-Old Skeleton Is Oldest Case Ever Found - ScienceAlert
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Anatomical and clinical aspects of Klinefelter's syndrome - Bird - 2016 - Clinical Anatomy - Wiley Online Library
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Spontaneous Pelvic Rupture as a Result of Renal Colic in a Patient with Klinefelter Syndrome - Wiley Online Library
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1,000-year-old skeleton with condition causing small testes uncovered - The Jerusalem Post
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Rett Symptoms Are Frequent in Klinefelter Syndrome Boys: Large Study - Rett Syndrome News
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Portal Vein Thrombosis Due to an Increase in Dose of Testosterone in a Young Man with Klinefelter Syndrome - Cureus
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Clinical research: Extra X increases risk of autism - The Transmitter
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Archaeologists didn't know why this man was so tall. It turns out he had an extra X chromosome - Australian Broadcasting Corporation
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Does Donald Trump Have Klinefelter Syndrome? - Snopes
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Facts on Klinefelter Syndrome (IMAGE) - EurekAlert!
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Succesful CPX-351 treatment of seminoma therapy-related acute myeloid leukemia in a patient with Klinefelter syndrome | Bujko-Wasiak | Acta Haematologica Polonica - Via Medica Journals
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A Simple Treatment Could Save Thousands of Lives – But Half Aren’t Getting It - SciTechDaily
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Are Adolescent Boys with Klinefelter Syndrome Androgen Deficient? A Longitudinal Study of Finnish 47,XXY Boys - Nature
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Births after Intracytoplasmic Injection of Sperm Obtained by Testicular Extraction from Men with Nonmosaic Klinefelter's Syndrome - NEJM
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eXtraordinarY: New clinic for X and Y chromosome variations | Emory University | Atlanta GA - Emory University
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Developing a new tool to detect a frequently missed sex chromosome disorder in boys - EurekAlert!
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CRISPR/Cas9 Eliminates Chromosomes - BioTechniques
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A Case Report of Exacerbation of Leg Ulcers Associated with Acute High-dose Acetylsalicylic Acid in a Patient with Klinefelter Syndrome - Cureus
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Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells - Nature
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News - Rare Genetic Condition Identified in 1,000-Year-Old Remains - Archaeology Magazine
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1,000-Year-Old Case of Syndrome Causing Small Testes Found in Portugal - Ancient Origins
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Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene-dose effect from the X chromosome - Wiley Online Library
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Developing a new tool to detect a frequently missed sex chromosome disorder in boys - Medical Xpress
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Oldest Case Of Rare Genetic Condition That Sees Males With Extra X Chromosome Discovered - IFLScience
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Mysterious Iron Age Burial May Hold Remains of Elite Nonbinary Person - Smithsonian Magazine
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Characterization of loss-of-inactive X in Klinefelter syndrome and female-derived cancer cells - Nature
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Testis Transcriptome Modulation in Klinefelter Patients with Hypospermatogenesis - Nature
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Klinefelter syndrome and mediastinal germ cell tumors - Völkl - 2006 - American Journal of Medical Genetics Part A - Wiley Online Library
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Self-help group for men with Klinefelter syndrome backs conclusions. - The BMJ
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Scientists may have found a way to overcome common genetic causes of male infertility - The Conversation
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