Why is "Ligand (biochemistry)" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-03-16 18:41:15
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Ligand_(biochemistry) entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-03-16 and was most recently seen on 2026-03-16.
Wikipedia Overview
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from Latin ligare, which means 'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a change of conformational isomerism (conformation) of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein which binds to the DNA double helix. The relationship between ligand and binding partner is a function of charge, hydrophobicity, and molecular structure.
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Trending Topic Today
Search Interest Perspective
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Inhibition of CREB Binding and Function with a Dual-Targeting Ligand - ACS Publications
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Hybrid hydrogel–extracellular matrix scaffolds identify biochemical and mechanical signatures of cardiac ageing - Nature
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Esteemed Molecular Biologist Named Winner of 2025 Kimberly Prize - Northwestern University
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Creating new chemistry tools | Chemistry & BioChemistry | Arts & Sciences - University of Delaware
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Ortlund Lab - Department of Biochemistry - Epitope Mapping - Emory School of Medicine
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Fine-Tuning Redox Properties of Heteroleptic Molybdenum Complexes through Ligand-Ligand-Cooperativity - Wiley Online Library
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Ligand Binding Introduces Significant Allosteric Shifts in the Locations of Protein Fluctuations - Frontiers
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Structural findings reveal how distinct GPCR ligands create different levels of activation [IMAGE] - EurekAlert!
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Pattern of Failure in Patients with Biochemical Recurrence After PSMA Radioguided Surgery - Journal of Nuclear Medicine
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Photoacoustic Calorimetry Studies of O2-Sensing FixL and (R200, I209) Variants from Sinorhizobium meliloti Reveal Conformational Changes Coupled to Ligand Photodissociation from the Heme-PAS Domain | Biochemistry - ACS Publications
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Dynamic biochemical tissue analysis detects functional selectin ligands on human cancer tissues - Nature
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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein - Wiley Online Library
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Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches - Frontiers
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(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5′-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect - ACS Publications
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X‐ray crystallographic of a novel pyrimidine ligand (LPH) and its metal chelates Cr3+, Ni2+, and Ru3+: A comprehensive study on synthesis, characterization, computational investigations, and biological evaluation toward anticancer and antioxidant - Wiley Online Library
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Cover Picture: [FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis (Angew. Chem. Int. Ed. 22/2022) - Wiley Online Library
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Unlocking a Ferrocenium Superoxidizer with the Perfluorinated Cp* Ligand - Wiley Online Library
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Ligand Effects in Regio- and Enantioselective Cobalt-Catalyzed Intramolecular [4+2]- and [2+2]-Cycloaddition Reactions of Unactivated 1,3-Diene-8-ynes and 1,3-Diene-8-enes - Wiley Online Library
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Asymmetric Dearomatization of Phenols via Ligand‐Enabled Cooperative Gold Catalysis - Wiley Online Library
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Early processes in heme-based CO-sensing proteins - Frontiers
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An original approach to measure ligand/receptor binding affinity in non-purified samples - Nature
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Attenuated G protein signaling and minimal receptor phosphorylation as a biochemical signature of low side-effect opioid analgesics - Nature
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Identification of small molecular inhibitors of SIRT3 by computational and biochemical approaches a potential target of breast cancer - Nature
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Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes - Wiley Online Library
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Celtarys, biochemistry at the service of new drug discovery - GCiencia
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Printed covalent glycan array for ligand profiling of diverse glycan binding proteins - PNAS
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NMR Spectroscopy Techniques for Screening and Identifying Ligand Binding to Protein Receptors - Wiley Online Library
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.