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Lois Patrice Griffin is a fictional character from the American animated television series Family Guy. She is voiced by Alex Borstein and first appeared in the show's pilot episode, "Death Has a Shadow", on January 31, 1999. Writer Seth MacFarlane created and designed Lois after his 1995 student film, The Life of Larry, was picked up by 20th Century Fox for a series order. Lois is the matriarch of the Griffin family. She and her husband Peter have three children: Meg, Chris, and Stewie.
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