Why is "N-Acetylserotonin" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-06 05:27:21
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
This topic is not currently in the ranking.
Wikipedia Overview
N-Acetylserotonin (NAS), also known as normelatonin, is a naturally occurring chemical intermediate in the endogenous production of melatonin from serotonin. It also has biological activity in its own right, including acting as a melatonin receptor agonist, an agonist of the TrkB, and having antioxidant effects.
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Trending Topic Today
Search Interest Perspective
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The serotonin- N -acetylserotonin–melatonin pathway as a biomarker for autism spectrum disorders - Nature
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N-Acetyl-Serotonin Offers Neuroprotection through Inhibiting Mitochondrial Death Pathways and Autophagic Activation in Experimental Models of Ischemic Injury - Journal of Neuroscience
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N-acetylserotonin promotes hippocampal neuroprogenitor cell proliferation in sleep-deprived mice - PNAS
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Identification of a serotonin N-acetyltransferase from Staphylococcus pseudintermedius ED99 - frontiersin.org
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Melatonin: A mitochondrial resident with a diverse skill set - ScienceDirect.com
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Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts - Wiley Online Library
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N -acetyl serotonin derivatives as potent neuroprotectants for retinas - PNAS
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Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress - Nature
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Distinct GmASMTs are involved in regulating transcription factors and signalling cross-talk across embryo development, biotic, and abiotic stress in soybean - frontiersin.org
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Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation - PNAS
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Microbial melatonin metabolism in the human intestine as a therapeutic target for dysbiosis and rhythm disorders - Nature
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Melatonin in Plants – Diversity of Levels and Multiplicity of Functions - frontiersin.org
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Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation - PNAS
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ASMT determines gut microbiota and increases neurobehavioral adaptability to exercise in female mice - Nature
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The role of phytomelatonin receptor 1-mediated signaling in plant growth and stress response - frontiersin.org
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Bumble bee queens activate dopamine production and gene expression in nutritional signaling pathways in the brain - Nature
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Enzyme Promiscuity in Serotonin Biosynthesis, From Bacteria to Plants and Humans - frontiersin.org
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The role of hydroxyindoles in protecting neuronal cultures from ferroptosis - Nature
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Understanding the mechanism of red light-induced melatonin biosynthesis facilitates the engineering of melatonin-enriched tomatoes - Nature
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The role of watermelon caffeic acid O -methyltransferase ( ClCOMT1 ) in melatonin biosynthesis and abiotic stress tolerance - Nature
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A de novo Transcriptome Assembly of the European Flounder (Platichthys flesus): The Preselection of Transcripts Encoding Active Forms of Enzymes - frontiersin.org
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Molecular cloning and functional analysis of serotonin N‐acetyltransferase from the cyanobacterium Synechocystis sp. PCC 6803 - Wiley Online Library
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Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia - Nature
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Probiotic may improve sleep quality: new research findings - EurekAlert!
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Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders - Nature
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Melatonin Modulates So Much More Than Just Sleep - Sleep Review
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Figure 3: Outline of Research Results (IMAGE) - EurekAlert!
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Study Suggests Cell Damage As Potential Danger Of Antibiotic Use - WBUR
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The Science of Sleep - Znaki FM
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.