Why is "Nociceptor" trending?

Search Interest Perspective

• Structural basis for agonist and heat activation of nociceptor TRPM3 - Nature
• Tumor-infiltrating nociceptor neurons promote immunosuppression - Science | AAAS
• Artificial pain sensing gets closer: One memristor links heat and touch responses - Tech Xplore
• Pain-Sensing Neurons Kick-Start Immune Responses - WCM Newsroom
• The Increased Activity of CaV3.2 Channels Contributes to Nociceptors’ Hyperexcitability and Chronic Neuropathic Pain Following Spinal Cord Injury in Mice - Journal of Neuroscience
• Molecular signature of sleeping nociceptors offers new pain targets - News-Medical
• Nociceptor-specific signaling of the receptor guanylyl cyclase Npr2 contributes to acute and persistent pain - Science | AAAS
• How should we define a nociceptor in the gut-brain axis? - Frontiers
• The psychoactive cannabinoid THC inhibits peripheral nociceptors by targeting Na - Nature
• Neurons modulate sensitivity via electron transport chain - The Transmitter
• Neutrophil-initiated nociceptive ingrowth orchestrates inflammation resolution to potentiate bone regeneration - Nature
• Nociceptor-immune interactomes reveal insult-specific immune signatures of pain - Nature
• Nociceptor neurons affect cancer immunosurveillance - Nature
• Nociceptor neurons promote PDAC progression and cancer pain by interaction with cancer-associated fibroblasts and suppression of natural killer cells - Nature
• Developing nociceptor-selective treatments for acute and chronic pain - Science | AAAS
• An artificial nociceptor based on a diffusive memristor - Nature
• Macrophages and nociceptor neurons form a sentinel unit around fenestrated capillaries to defend the synovium from circulating immune challenge - Nature
• Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice - Science | AAAS
• Multimodal control of dendritic cell functions by nociceptors - Science | AAAS
• Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia - Nature
• Presynaptic NMDARs on spinal nociceptor terminals state-dependently modulate synaptic transmission and pain - Nature
• Scientists design artificial pain receptor that senses pain intensity and self-heals - Phys.org
• Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain - PNAS
• The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females - Science | AAAS
• House dust mites activate nociceptor–mast cell clusters to drive type 2 skin inflammation - Nature
• Activation of TRPA1 nociceptor promotes systemic adult mammalian skin regeneration - Science | AAAS
• No pain, no gain — how nociceptors orchestrate tissue repair - Nature
• The Nociceptor Primary Cilium Contributes to Mechanical Nociceptive Threshold and Inflammatory and Neuropathic Pain - Journal of Neuroscience
• Nociceptor sensitization in pain pathogenesis - Nature
• Membrane lipid nanodomains modulate HCN pacemaker channels in nociceptor DRG neurons - Nature
• Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts - Nature
• The single-cell transcriptomic atlas iPain identifies senescence of nociceptors as a therapeutical target for chronic pain treatment - Nature
• Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord - Nature
• Sex-specific nociceptor modulation of the apical periodontitis transcriptome - Frontiers
• Inhibiting endocytosis in CGRP+ nociceptors attenuates inflammatory pain-like behavior | Nature Communications - Nature
• Nociceptor nerves set the stage for skin immunity - Nature
• Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis - Nature
• Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain - Nature
• Nociceptor sodium channels shape subthreshold phase, upstroke, and shoulder of action potentials - Rockefeller University Press
• A role for nociceptor neurons in gut defence - Nature
• Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing - Frontiers
• Distinct Terminal and Cell Body Mechanisms in the Nociceptor Mediate Hyperalgesic Priming - Journal of Neuroscience
• Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors - Science | AAAS
• Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain - Journal of Neuroscience
• Neuroanatomical and neurophysiological evidence of pulmonary nociceptor and carotid chemoreceptor convergence in the nucleus tractus solitarius and nucleus ambiguus - American Physiological Society Journal
• A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1 - Nature
• Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli - Frontiers
• TRPC3/6 Channels Mediate Mechanical Pain Hypersensitivity via Enhancement of Nociceptor Excitability and of Spinal Synaptic Transmission - Wiley
• A triplex for intestinal protection: Neurons, microbes, and goblet cells - sciencedirect.com
• Preferential C-nociceptor stimulation facilitates peripheral axon reflex flare, but not secondary mechanical hyperalgesia - Frontiers
• Granulocyte-Macrophage Colony Stimulating Factor As an Indirect Mediator of Nociceptor Activation and Pain - Journal of Neuroscience
• Innate Receptors Expression by Lung Nociceptors: Impact on COVID-19 and Aging - Frontiers
• A master regulator of nociceptor differentiation - Nature
• The Role of Kv7/M Potassium Channels in Controlling Ectopic Firing in Nociceptors - Frontiers
• Defending the gut - Nature
• Sharpness recognition based on synergy between bio-inspired nociceptors and tactile mechanoreceptors - Nature
• The Input-Output Relation of Primary Nociceptive Neurons is Determined by the Morphology of the Peripheral Nociceptive Terminals - Journal of Neuroscience
• Epineural optogenetic activation of nociceptors initiates and amplifies inflammation - Nature
• Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception - Nature
• Study shows first evidence of sex differences in how pain can be produced - The University of Arizona Health Sciences
• Gut nociceptors: sentinels promoting host defense - Nature
• Primary Afferent Nociceptor as a Target for the Relief of Pain - Parada - 2012 - Pain Research and Treatment - onlinelibrary.wiley.com
• A Probabilistic Model for Estimating the Depth and Threshold Temperature of C-fiber Nociceptors - Nature
• Author Correction: Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia - Nature
• Squid Have Nociceptors That Display Widespread Long-Term Sensitization and Spontaneous Activity after Bodily Injury - Journal of Neuroscience
• Pain research in 2022: nociceptors and central sensitisation - The Lancet
• From pain to meningitis: bacteria hijack nociceptors to promote meningitis - Frontiers
• A subpopulation of nociceptors specifically linked to itch - Nature
• Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers - Nature
• Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors - Nature
• Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection - Nature
• Identification of functional sex differences in nociceptors - Drug Target Review
• When Differential Descending Control of Speed Matters: Descending Modulation of A- versus C-Fiber Evoked Spinal Nociception - Frontiers
• Optogenetic activation of mechanical nociceptions to enhance implant osseointegration - Nature
• Neuroscientist Leads National Project on Pain’s Molecular Origins - The University of Texas at Dallas
• Zcchc12 -Containing Nociceptors Are Required for Noxious Heat Sensation - Journal of Neuroscience
• Type I Interferons Act Directly on Nociceptors to Produce Pain Sensitization: Implications for Viral Infection-Induced Pain - Journal of Neuroscience
• An Artificial Mechano‐Nociceptor with Mott Transition - Kumar - 2021 - Small Methods - onlinelibrary.wiley.com
• Differences between Dorsal Root and Trigeminal Ganglion Nociceptors in Mice Revealed by Translational Profiling - Journal of Neuroscience
• Opening of an alternative ion permeation pathway in a nociceptor TRP channel - Nature
• Opioid-Induced Hyperalgesic Priming in Single Nociceptors - Journal of Neuroscience
• A Role for K2P Channels in the Operation of Somatosensory Nociceptors - Frontiers
• Studying Independent Kcna6 Knock-out Mice Reveals Toxicity of Exogenous LacZ to Central Nociceptor Terminals and Differential Effects of Kv1.6 on Acute and Neuropathic Pain Sensation - Journal of Neuroscience
• Control of myeloid cell functions by nociceptors - Frontiers
• FABP5 deletion in nociceptors augments endocannabinoid signaling and suppresses TRPV1 sensitization and inflammatory pain - Nature
• Persistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation - Journal of Neuroscience
• How Cells in the Skin Team Up To Fight Pathogens - the-scientist.com
• Identification of key factors driving inflammation-induced sensitization of muscle sensory neurons - Frontiers
• Nociceptor plasticity: A closer look - onlinelibrary.wiley.com
• Enteric glia promote visceral hypersensitivity during inflammation through intercellular signaling with gut nociceptors - Science | AAAS
• The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1 - Journal of Neuroscience
• Inflammatory sensitization of nociceptors depends on activation of NMDA receptors in DRG satellite cells - PNAS
• Human Brain Responses to Concomitant Stimulation of Aδ and C Nociceptors - Journal of Neuroscience
• TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour - Nature
• Nociceptor and Hair Cell Transducer Properties of TRPA1, a Channel for Pain and Hearing - Journal of Neuroscience
• Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds - Journal of Neuroscience
• PI3Kγ/AKT Signaling in High Molecular Weight Hyaluronan (HMWH)-Induced Anti-Hyperalgesia and Reversal of Nociceptor Sensitization - Journal of Neuroscience
• Targeting Ion Channels to Manage Osteoarthritis Pain - Northwestern University
• Study shows first evidence of sex differences in how pain can be produced - Medical Xpress
• αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors - PNAS