Why is "Nucleotide" trending?

Search Interest Perspective

• A single-nucleotide enhancer mutation overrides chromosomal sex to drive XX male development - Nature
• Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesity - Science | AAAS
• PCNA is a nucleotide exchange factor for the clamp loader ATPase complex - PNAS
• Probing the Chemical Space of Polymerase Theta with Nucleotide Analogues Bearing a Stereogenic All-Carbon Quaternary Center - ACS Publications
• Impact of the Warburg effect on nucleotide homeostasis in human retinal endothelial cells and its relevance to proliferative diabetic retinopathy - Frontiers
• Understanding the link between nucleotide metabolism and chromatin assembly - Phys.org
• Zhen-Ao Group Showcases Core 5'-Nucleotide Breakthroughs in Cambridge, Illuminating a Chinese Path for Global Technology-Driven Anti-Aging - The Manila Times
• Arabidopsis thaliana Cyclic Nucleotide-Gated Channel 19 is involved in root extracellular ATP and Pep1 signalling - Wiley
• Tiny DNA tweak flips biological sex, researchers report - The Jerusalem Post
• Patch type nucleotide sequence identities between genomes from many different species facilitate illegitimate recombination - Nature
• Nucleotides on the frontline: Nucleotide-centric defense systems reveal a core principle in bacterial antiviral immunity - Science | AAAS
• Targeting energy, nucleotide, and DNA synthesis in cancer - Frontiers
• Functional dissection of complex trait variants at single-nucleotide resolution - Nature
• Pre-incision structures reveal principles of DNA nucleotide excision repair - Nature
• Nucleotide dependency analysis of genomic language models detects functional elements - Nature
• Annotating the genome at single-nucleotide resolution with DNA foundation models - Nature
• Structural snapshots capture nucleotide release at the μ-opioid receptor - Nature
• Increased nucleotide metabolism alleviates Alzheimer’s disease pathology - Nature
• Classically activated macrophages undergo functionally significant nucleotide metabolism remodelling driven by nitric oxide - Nature
• Microtubules in the axon are GDP bound but adopt a stable GTP-like expanded state - Nature
• Identification of a key nucleotide influencing Cas12a crRNA activity for universal photo-controlled CRISPR diagnostics - Nature
• Single Nucleotide SMN1 Variants in a Cohort of Individuals With Spinal Muscular Atrophy - Neurology® Journals
• Evaluating single nucleotide polymorphisms in beta - 2 - microglobulin – a theoretical study - Frontiers
• Case Report: Association of a rare single nucleotide variant in the KCNH2 gene with drug-induced QT prolongation - Frontiers
• Accurate and rapid single nucleotide variation detection in PCSK9 gene using nanopore sequencing - Frontiers
• Construction and application of multiple nucleotide polymorphism-based DNA fingerprinting for Polygonatum cyrtonema identification - Frontiers
• Atomistic mechanism of non-selective cation permeation in cyclic nucleotide-gated CNGA1 ion channel by molecular dynamics simulations - Nature
• Roles of nucleotide metabolism in pancreatic cancer - Frontiers
• Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain - Nature
• A single-nucleotide mutation of G301A in GaIAA14 confers leaf curling in Gossypium arboreum - Frontiers
• Editorial: Guanine nucleotide exchange factors as determinants of cell fate and development - Frontiers
• Nucleotide Transformer: building and evaluating robust foundation models for human genomics - Nature
• Direct stimulation of de novo nucleotide synthesis by O -GlcNAcylation - Nature
• Nucleotide imbalance decouples cell growth from cell proliferation - Nature
• NucleoTide – CRISPR-based biosensors for rapidly detecting harmful marine microbes - Wyss Institute at Harvard
• The latest on nucleotide therapy development - Nature
• Nucleotide metabolism: a pan-cancer metabolic dependency - Nature
• Rapid repair of human disease-specific single-nucleotide variants by One-SHOT genome editing - Nature
• Enhancing nucleotide sequence representations in genomic analysis with contrastive optimization - Nature
• Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ - Nature
• Single nucleotide translation without ribosomes - Nature
• Indexing and searching petabase-scale nucleotide resources - Nature
• A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy - PNAS
• Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes - Nature
• Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage - Rockefeller University Press
• A catalog of single nucleotide changes distinguishing modern humans from archaic hominins - Nature
• Nucleotide-mediated modulation of chemoselective protein functionalization in a liquid-like condensed phase - Nature
• Integrated synthesis of nucleotide and nucleosides influenced by amino acids - Nature
• Molecular mechanisms underlying nucleotide repeat expansion disorders - Nature
• Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore - PNAS
• Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells - Nature
• Base-modified nucleotides mediate immune signaling in bacteria - Science | AAAS
• Bending forces and nucleotide state jointly regulate F-actin structure - Nature
• Four-color DNA sequencing with 3′-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides - PNAS
• The Arabidopsis dnd1 “defense, no death” gene encodes a mutated cyclic nucleotide-gated ion channel - PNAS
• A single-nucleotide change underlies the genetic assimilation of a plastic trait - Science | AAAS
• A nucleotide binding–independent role for γ-tubulin in microtubule capping and cell division - Rockefeller University Press
• 6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution - Science | AAAS
• Bacterial cGAS-like enzymes synthesize diverse nucleotide signals - Nature
• Structural Basis of Transcription: Nucleotide Selection by Rotation in the RNA Polymerase II Active Center - ScienceDirect.com
• Deadenylation kinetics of mixed poly(A) tails at single-nucleotide resolution - Nature
• De novo DNA synthesis using polymerase-nucleotide conjugates - Nature
• Energy efficiency trade-offs drive nucleotide usage in transcribed regions - Nature
• Population-wide DNA methylation polymorphisms at single-nucleotide resolution in 207 cotton accessions reveal epigenomic contributions to complex traits - Nature
• The hepatic clock synergizes with HIF-1α to regulate nucleotide availability during liver damage repair - Nature
• An Overlooked Nucleotide Recycling Pathway Fuels Tumor Growth - the-scientist.com
• A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases - Nature
• Generative language models on nucleotide sequences of human genes - Nature
• Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response - Science | AAAS
• Life as a guide to prebiotic nucleotide synthesis - Nature
• Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer - Nature
• Towards inferring nanopore sequencing ionic currents from nucleotide chemical structures - Nature
• The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus - PNAS
• An Overlooked Prebiotic: Beneficial Effect of Dietary Nucleotide Supplementation on Gut Microbiota and Metabolites in Senescence-Accelerated Mouse Prone-8 Mice - Frontiers
• Long-Read-Resolved, Ecosystem-Wide Exploration of Nucleotide and Structural Microdiversity of Lake Bacterioplankton Genomes - ASM Journals
• Freeze-thaw cycles enable a prebiotically plausible and continuous pathway from nucleotide activation to nonenzymatic RNA copying - PNAS
• Indirect activation of a plant nucleotide binding site–leucine-rich repeat protein by a bacterial protease - PNAS
• Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity - PNAS
• A TriPPPro‐Nucleotide Reporter with Optimized Cell‐Permeable Dyes for Metabolic Labeling of Cellular and Viral DNA in Living Cells - Wiley Online Library
• An approach for global scanning of single nucleotide variations - PNAS
• Bound nucleotide can control the dynamic architecture of monomeric actin - Nature
• A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome - Nature
• Genome-wide role of Rad26 in promoting transcription-coupled nucleotide excision repair in yeast chromatin - PNAS
• Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure - Frontiers
• RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription - PNAS
• Ab Initio investigation for DNA nucleotide bases sequencing using chiral carbon nanobelts and nanotubes - Nature
• MIG-seq: an effective PCR-based method for genome-wide single-nucleotide polymorphism genotyping using the next-generation sequencing platform - Nature
• Structural Investigation of Park’s Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors - Nature
• Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos - Science | AAAS
• Engineering of high-precision base editors for site-specific single nucleotide replacement - Nature
• Extensive free-energy simulations identify water as the base in nucleotide addition by DNA polymerase - PNAS
• RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma - Wiley
• Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange - PNAS
• Synthesis of Nucleoside and Nucleotide Analogues by Cyclization of the Guanine Base with 1,1,3,3-Tetramethoxypropane - ACS Publications
• Cancer Cells Hijack Nucleotide Metabolism to Boost Cell Proliferation - Northwestern University
• An orally available non-nucleotide STING agonist with antitumor activity - Science | AAAS
• Independent and simultaneous translocation of two substrates by a nucleotide sugar transporter - PNAS
• Suppressing a phosphohydrolase of cytokinin nucleotide enhances grain yield in rice - Nature
• Understanding nucleotide excision repair and its roles in cancer and ageing - Nature
• On the comparison of population-level estimates of haplotype and nucleotide diversity: a case study using the gene cox1 in animals - Nature