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The paramedian pontine reticular formation (PPRF) is a subset of neurons of the oral and caudal pontine reticular nuclei. With the abducens nucleus it makes up the horizontal gaze centre. It is situated in the pons adjacent to the abducens nucleus. It projects to the ipsilateral abducens nucleus, and contralateral oculomotor nucleus to mediate conjugate horizontal gaze and saccades.
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