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This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
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This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-06-05 and was most recently seen on 2026-06-05.
Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by host bacteria when infected with bacteriophages in order to cleave the cell wall during the final stage of the lytic cycle to release the viral particles. Lysins are highly evolved enzymes that are able to target one of the five bonds in peptidoglycan (murein), the main component of bacterial cell walls, which allows the release of progeny virions from the lysed cell. Cell-wall-containing Archaea are also lysed by specialized pseudomurein-cleaving lysins, while most archaeal viruses employ alternative mechanisms. Similarly, not all bacteriophages synthesize lysins: some small single-stranded DNA and RNA phages produce membrane proteins that activate the host's autolytic mechanisms such as autolysins.
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