Why is "Phenethylamine" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-30 23:03:30
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Phenethylamine entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-30 and was most recently seen on 2026-04-30.
Wikipedia Overview
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter in the human central nervous system. In mammals, phenethylamine is produced from the amino acid L-phenylalanine by the enzyme aromatic L-amino acid decarboxylase via enzymatic decarboxylation. In addition to its presence in mammals, phenethylamine is found in many other organisms and foods, such as chocolate, especially after microbial fermentation.
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Trending Topic Today
Search Interest Perspective
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The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents | Molecular Psychiatry - Nature
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Phenylethylamine is Said To Stoke the Fire of Love. Here Comes the Water Bucket. - McGill University
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β -Phenethylamine Synthesis: N -Pyridinium Aziridines as Latent Dual Electrophiles - Wiley Online Library
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Phenethylamine in chlorella alleviates high-fat diet-induced mouse liver damage by regulating generation of methylglyoxal | npj Science of Food - Nature
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Aziridine Opening via a Phenonium Ion Enables Synthesis of Complex Phenethylamine Derivatives - ACS Publications
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This is your brain on love - www.heart.org
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Why a Workout Makes You Happy - Science | AAAS
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Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome - Nature
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meta‐Selective C−H Borylation of Benzylamine‐, Phenethylamine‐, and Phenylpropylamine‐Derived Amides Enabled by a Single Anionic Ligand - Davis - 2017 - Angewandte Chemie International Edition - Wiley Online Library
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Phenethylamine is a substrate of monoamine oxidase B in the paraventricular thalamic nucleus - Nature
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Synthesis of Phenethylamine-Azulene Conjugates Enabled by Regioselective Ring Opening of Aziridines - Wiley
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ADME of Bromo-DragonFLY as an example of a new psychoactive substance (NPS) – application of in Silico methods for prediction: absorption, distribution, metabolism and excretion - Nature
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anti -Markovnikov Hydroamination of Alkenes Catalyzed by a Two-Component Organic Photoredox System: Direct Access to Phenethylamine Derivatives - Wiley Online Library
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Chronic Phenethylamine Hallucinogen Treatment Alters Behavioral Sensitivity to a Metabotropic Glutamate 2/3 Receptor Agonist - Nature
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Aminopotassiation by Mixed Potassium/Lithium Amides: A Synthetic Path to Difficult to Access Phenethylamine Derivates - Wiley Online Library
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New phenethylamine derivatives from Arenibacter nanhaiticus sp. nov. NH36A - Nature
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Degradation Mechanism of Phenethylamine-Based Interlayers in Perovskite Solar Cells and Breakthrough - Wiley Online Library
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The effect of novel β-lactam derivatives synthesized from substituted phenethylamines on resistance genes of MRSA isolates - Nature
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The 4-alkyl chain length of 2,5-dimethoxyamphetamines differentially affects in vitro serotonin receptor actions versus in vivo psychedelic-like effects | Molecular Psychiatry - Nature
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MDMA in Psychiatry: Past, Present, and Future - Psychiatry Online
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A molecular analysis of substituted phenylethylamines as potential microtubule targeting agents through in silico methods and in vitro microtubule-polymerization activity - Nature
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anti -Markovnikov Hydroamination of Alkenes Catalyzed by a Two-Component Organic Photoredox System: Direct Access to Phenethylamine Derivatives - Wiley Online Library
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October 2019 - WHO: NPS to be reviewed for potential scheduling under the International Drug Control Conventions - United Nations Office on Drugs & Crime
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News: October 2014 - UNODC-EWA: 25I-NBOMe is the most reported substance in 2014 - United Nations Office on Drugs & Crime
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October 2014 - UNODC-EWA: Synthetic cannabinoids are the fastest growing NPS group in 2014 - United Nations Office on Drugs & Crime
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The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system - PNAS
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Hidden Speed: What Is BMPEA and Why Is It Dangerous? - NBC News
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Recognition of 1-phenylethylamine enantiomers by thin solid films of inherently chiral calix[4]arene - Wiley Online Library
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HKBU-led research discovers new therapeutic target for irritable bowel syndrome - Asia Research News |
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Reference Standards for Designer Psychedelics - Clinical Lab Products
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Fort Myers man sentenced to 25 years in prison for drug trafficking, ordered to pay $900K in fines - Gulf Coast News and Weather
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New drugs that parents should be aware of - Central New Jersey News
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A rodent-repelling odor - C&EN
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Supplements Marketed to Military Contain Dangerous, Illegal Substances - U.S. Medicine
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Chemistry/structural biology of psychedelic drugs and their receptor(s) - British Pharmacological Society | Journals
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Michigan begins process to make new synthetic drug illegal - Coldwater Daily Reporter
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DEA Judge Backs Federal Ban On 2 Research Chemicals - Law360
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Herbal amphetamine: Denmark takes heed of Swedish warning - NutraIngredients.com
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Medsafe: Do not consume this coffee product - The Central App
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Fort Myers police arrest 18 in undercover operation targeting drug trafficking, illegal gun sales - Gulf Coast News and Weather
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Serotonin and Hallucinogens - Neuropsychopharmacology - Nature
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9 members of Fort Myers drug trafficking ring arrested, over $162K worth of drugs seized - Gulf Coast News and Weather
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Can Chocolate Give Me a Happy-high? - HowStuffWorks
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Dark Chocolate May Help with Parkinson's Disease Symptoms - Parkinson's News Today
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Legal highs: what you need to know - Channel 4
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Hi-Tech Responds To "Bullying Tactics" Issued By FDA On Acacia Rigidula - BioSpace
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Al-Ittihad star Al-Mowallad faces ban for doping - Arab News
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Does your sports supplement contain illegal drugs? - Consumer NZ
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MPs vote in favour of wider designer drug ban - DutchNews.nl
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Review of issues related to AMPK activators and stimulant ingredients - SupplySide Supplement Journal
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NBOMes–Highly Potent and Toxic Alternatives of LSD - Frontiers
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Why Venom Needs a Host to Survive in Marvel Lore - ScreenRant
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Hi-Tech Pharmaceuticals Thermo-Rx® brand Senegalia Berlandieri Extract is Most Effective Weight Loss Ingredient Available! - BioSpace
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New substances added to prohibited drug list - Gulf News
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Hong Kong Baptist University-led research discovers new therapeutic target for irritable bowel syndrome - Media OutReach Newswire
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Could chocolate be used to treat Parkinson’s? - News24
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.