Why is "RNA interference" trending?
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Trend Analysis
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- Date: 2026-04-01 18:35:44
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by other names, including co-suppression, post-transcriptional gene silencing (PTGS), and quelling. The detailed study of each of these seemingly different processes elucidated that the identity of these phenomena were all actually RNAi. Andrew Fire and Craig Mello shared the 2006 Nobel Prize in Physiology or Medicine for their work on RNAi in the nematode worm Caenorhabditis elegans, which they published in 1998. Since the discovery of RNAi and its regulatory potentials, it has become evident that RNAi has immense potential in suppression of desired genes. RNAi is now known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector may be developed and find utility as novel therapeutic agents.
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Trending Topic Today
Search Interest Perspective
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Cross-kingdom RNA interference promotes arbuscular mycorrhiza development - Nature
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RNA interference shapes stress responses in Arabidopsis thaliana - Frontiers
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Knockdown of AisHSP19.6 by RNA Interference Increases Susceptibility to Three Insecticides in Agrotis ipsilon - Wiley Online Library
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Aerska raises US$39m for RNA interference drugs - Health Tech World
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New Thrombosis Safety Data for RNA Interference Agent to Treat Bleeding Disorders - Docwire News
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Fungal Argonaute proteins act in bidirectional cross-kingdom RNA interference during plant infection - PNAS
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MicroRNA (miRNA) | Description, Discovery, Function, & Role in Disease - Britannica
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RNA interference and turnover in plants -a complex partnership - Frontiers
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What Is RNAi? Gene Silencing Explained for Researchers and Innovators - the-scientist.com
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Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension - NEJM
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Explained: RNA interference - MIT News
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Conditional RNA interference in mammalian cells via RNA transactivation - Nature
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RNA Interference Therapy Targeting Apolipoprotein C-III in Hypertriglyceridemia - NEJM Evidence
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RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells - PNAS
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Conserved chromosomal functions of RNA interference - Nature
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RNA Interference as a Prospective Tool for the Control of Human Viral Infections - Frontiers
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Using RNA interference to identify genes required for RNA interference - PNAS
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Therapeutic Potential of RNA Interference - NEJM
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Identification of positive and negative regulators of antiviral RNA interference in Arabidopsis thaliana - Nature
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Strategies for silencing human disease using RNA interference - Nature
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Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia - NEJM
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RNA interference in the era of nucleic acid therapeutics - Nature
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Active RNA interference in mitochondria - Nature
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RNA Interference (RNAi) in gene silencing - Nature
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Pupal RNA interference methods for analyzing adult development in stag beetles - Wiley Online Library
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Functional specialization among insect chitinase family genes revealed by RNA interference - PNAS
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Key Mechanistic Principles and Considerations Concerning RNA Interference - Frontiers
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RNA therapeutics: beyond RNA interference and antisense oligonucleotides - Nature
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RNA interference protocols for gene silencing in the spittlebug Philaenus spumarius , vector of Xylella fastidiosa - Nature
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RNA Interference in Insects: Protecting Beneficials and Controlling Pests - Frontiers
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RNA interference in insects: the link between antiviral defense and pest control - Wiley Online Library
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RNA interference core components identified and characterised in Verticillium nonalfalfae , a vascular wilt pathogenic plant fungi of hops - Nature
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RNA interference in three humans - Nature
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Foliar application of clay-delivered RNA interference for whitefly control - Nature
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RNA Interference in the Nucleus - Science | AAAS
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Approval of first ‘RNA interference’ drug – why the excitement? - The Conversation
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RNA interference-independent reprogramming of DNA methylation in Arabidopsis - Nature
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RNA Interference and Nanotechnology: A Promising Alliance for Next Generation Cancer Therapeutics - Frontiers
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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells - PNAS
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Genome-scale RNA interference profiling of Trypanosoma brucei cell cycle progression defects - Nature
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Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways - Science | AAAS
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Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation - PNAS
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Research progress and limitation analysis of RNA interference in Haemonchus contortus in China - Frontiers
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Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans - PNAS
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RNA Interference Research Report 2024: Global Market to Surpass $6.5 Billion by 2034, Fueled by Advancements in Delivery, Rising Investments, Strategic Collaborations, Government & Regulatory Backing - ResearchAndMarkets.com - Business Wire
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RNA Interference in the Tobacco Hornworm, Manduca sexta, Using Plastid-Encoded Long Double-Stranded RNA - Frontiers
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Caenorhabditis elegans inositol hexaphosphate pathways couple to RNA interference and pathogen defense - PNAS
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Investors flee as firm scraps RNA-interference drug candidate - Nature
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ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos - PNAS
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Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria - NEJM
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Study Provides Proof in Humans of RNA Interference Using Targeted Nanoparticles - UCLA Health
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The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo - PNAS
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Mitochondrially mediated RNA interference, a retrograde signaling system affecting nuclear gene expression - Nature
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Leveraging RNA interference technology for selective and sustainable crop protection - Frontiers
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Interplay between RNA interference and transposable elements in mammals - Frontiers
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Better RNA interference, inspired by nature - MIT News
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In Vivo Imaging of RNA Interference - Journal of Nuclear Medicine
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Generation of siRNA Nanosheets for Efficient RNA Interference - Nature
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Long DCL4-substrate dsRNAs efficiently induce RNA interference in plant cells - Nature
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Germline AGO2 mutations impair RNA interference and human neurological development - Nature
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Next-generation libraries for robust RNA interference-based genome-wide screens - PNAS
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Silencing of genes in cultured Drosophila neurons by RNA interference - PNAS
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Cross-kingdom RNA interference mediated by insect salivary microRNAs may suppress plant immunity - PNAS
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RNA Interference for Improving Disease Resistance in Plants and Its Relevance in This Clustered Regularly Interspaced Short Palindromic Repeats-Dominated Era in Terms of dsRNA-Based Biopesticides - Frontiers
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Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways - PNAS
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Transfer RNA and Origins of RNA Interference - Frontiers
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Next-Generation Lipids in RNA Interference Therapeutics - ACS Publications
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Environmental RNA interference in two-spotted spider mite, Tetranychus urticae , reveals dsRNA processing requirements for efficient RNAi response - Nature
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The Delivery of RNA-Interference Therapies Based on Engineered Hydrogels for Bone Tissue Regeneration - Frontiers
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Systematic RNA interference reveals that oncogenic KRAS -driven cancers require TBK1 - Nature
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Mechanism of RNA interference discovered - Nature
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#VisualAbstract: Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension - 2 Minute Medicine
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RNA Interference-Induced Innate Immunity, Off-Target Effect, or Immune Adjuvant? - Frontiers
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Current prospects for RNA interference-based therapies - Nature
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Dissecting self-renewal in stem cells with RNA interference - Nature
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From guide to target: molecular insights into eukaryotic RNA-interference machinery - Nature
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Is RNA Interference a Physiologically Relevant Innate Antiviral Immune Response in Mammals? - ScienceDirect.com
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Genes required for Drosophila nervous system development identified by RNA interference - PNAS
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The coming of age story of RNAi technology - Labiotech.eu
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Cell microarrays and RNA interference chip away at gene function - Nature
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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells - Nature
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Developing RNA Interference to Control Zebra Mussels - USGS (.gov)
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Natural RNA interference directs a heritable response to the environment - Nature
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Protection against lethal influenza virus challenge by RNA interference in vivo - PNAS
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Application of RNA interference and protein localization to investigate housekeeping and developmentally regulated genes in the emerging model protozoan Paramecium caudatum - Nature
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NIR Light-Mediated Mitochondrial RNA Modification for Cancer RNA Interference Therapeutics - Wiley Online Library
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Viruses and RNA Interference: Issues and Controversies - ASM Journals
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A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA - Science | AAAS
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Self-assembled RNA interference microsponges for efficient siRNA delivery - Nature
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Genome-wide RNA interference screening reveals a COPI-MAP2K3 pathway required for YAP regulation - PNAS
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Targeted delivery methods for RNA interference are necessary to obtain a potential functional cure for HIV/AIDS - ScienceDirect.com
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siRNA Design Software for a Target Gene-Specific RNA Interference - Frontiers
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The Promise of RNA Interference (RNAi) Therapies: Revolutionizing Medicine - Pharmacy Times
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Inhibition of influenza virus production in virus-infected mice by RNA interference - PNAS
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RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee - PNAS
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RNA interference and validation of reference genes for gene expression analyses using qPCR in southern pine beetle, Dendroctonus frontalis - Nature
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RNA interference: genetic wand and genetic watchdog - Nature
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The challenge of delivering RNA-interference therapeutics to their target cells - Nature
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A transgenic approach for RNA interference-based genetic screening in mice - PNAS
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RNA interference of trehalose-6-phosphate synthase and trehalase genes regulates chitin metabolism in two color morphs of Acyrthosiphon pisum Harris - Nature
Why This Topic Is Trending
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