Why is "Replisome" trending?

Search Interest Perspective

• An orthogonal T7 replisome for continuous hypermutation and accelerated evolution in E. coli - Science | AAAS
• Rescuing the bacterial replisome at a nick requires recombinational repair and helicase reloading - Nature
• The bacteriophage T4 replisome: a model system for understanding DNA replication mechanisms - ASM Journals
• Scientists build an “evolution engine” to rapidly reprogram proteins - Scripps Research
• Genome integrity relies on rapid recycling of DNA Pol III in bacteria - PNAS
• Replisomes restrict SMC translocation in vivo - Nature
• Mechanisms for Maintaining Eukaryotic Replisome Progression in the Presence of DNA Damage - Frontiers
• CFAP20 salvages arrested RNAPII from the path of co-directional replisomes - Nature
• G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation - Science | AAAS
• Observing protein dynamics during DNA-lesion bypass by the replisome - Frontiers
• USP37 prevents premature disassembly of stressed replisomes by TRAIP - Nature
• Structures and operating principles of the replisome - Science | AAAS
• USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination - Nature
• PAF15–PCNA exhaustion governs the strand-specific control of DNA replication - Nature
• RNA polymerase II is a polar roadblock to a progressing DNA fork - Nature
• Chromosome organization shapes replisome dynamics in Caulobacter crescentus - Nature
• A conserved mechanism for regulating replisome disassembly in eukaryotes - Nature
• The Escherichia coli chromosome moves to the replisome - Nature
• RTF2 controls replication repriming and ribonucleotide excision at the replisome - Nature
• Plasmid hypermutation using a targeted artificial DNA replisome - Science | AAAS
• Single-molecule analysis reveals that the lagging strand increases replisome processivity but slows replication fork progression - PNAS
• Communication between DNA polymerases and Replication Protein A within the archaeal replisome - Nature
• Redox-sensitive alteration of replisome architecture safeguards genome integrity - Science | AAAS
• Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange - PNAS
• DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis - Nature
• Replisome speed determines the efficiency of the Tus− Ter replication termination barrier - Nature
• The Fate of Two Unstoppable Trains After Arriving Destination: Replisome Disassembly During DNA Replication Termination - Frontiers
• Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome - PNAS
• T7 replisome directly overcomes DNA damage - Nature
• Oxidative DNA damage stalls the human mitochondrial replisome - Nature
• Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome - Nature
• LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components - Rockefeller University Press
• Fission Yeast Sirtuin Hst4 Functions in Preserving Genomic Integrity by Regulating Replisome Component Mcl1 - Nature
• Replication of the Mammalian Genome by Replisomes Specific for Euchromatin and Heterochromatin - Frontiers
• Synergism between CMG helicase and leading strand DNA polymerase at replication fork - Nature
• A Replisome’s journey through the bacterial chromosome - Frontiers
• Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome - Nature
• A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome - Nature
• Direct observation of independently moving replisomes in Escherichia coli - Nature
• Polyubiquitylation drives replisome disassembly at the termination of DNA replication - Science | AAAS
• Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes - Nature
• Replisome Dynamics during Chromosome Duplication - ASM Journals
• Nucleosomes represent a crucial target for the intra-S phase checkpoint in response to replication stress - Science | AAAS
• Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis - PNAS
• GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks - Nature
• Replisome assembly and the direct restart of stalled replication forks - Nature
• The replisome uses mRNA as a primer after colliding with RNA polymerase - Nature
• Two paths to let the replisome go - Nature
• Understanding how the replisome works - Nature
• DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain - Nature
• Fast and efficient DNA replication with purified human proteins - Nature
• When Multi-Subunit Complexes Meet: Replisome-Cohesin Interactions at the Replication Fork - Advanced Science News
• Seeing a molecular machine self-renew - PNAS
• The mechanism of replication stalling and recovery within repetitive DNA - Nature
• How DNA protein machines collide head-on and stop replication - UW Medicine | Newsroom
• Helicase promotes replication re-initiation from an RNA transcript - Nature
• The intra-S phase checkpoint directly regulates replication elongation to preserve the integrity of stalled replisomes - PNAS
• Research Team Achieves First Image of Molecular Machinery that Copies DNA - SBU News
• Study reveals the architecture of the molecular machine that copies DNA - Phys.org
• Unwinding of a eukaryotic origin of replication visualized by cryo-EM - Nature
• EEPD1: Breaking and Rescuing the Replication Fork - PLOS
• CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome - PNAS
• Decades Old DNA Replication Models Called into Question - Genetic Engineering and Biotechnology News
• First complete pictures of cells' DNA-copying machinery - EurekAlert!
• Scientists unwind mystery behind DNA replication - Cornell University
• DNA replication at high res - Nature
• Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli - Nature
• Stoichiometry and Architecture of Active DNA Replication Machinery in Escherichia coli - Science | AAAS
• Primer release is the rate-limiting event in lagging-strand synthesis mediated by the T7 replisome - PNAS
• RecA acts as a switch to regulate polymerase occupancy in a moving replication fork - PNAS
• Arranging eukaryotic nuclear DNA polymerases for replication - Kunkel - 2017 - BioEssays - Wiley Online Library
• Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis - Science | AAAS
• Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling - Nature
• BLM Sumoylation Is Required for Replication Stability and Normal Fork Velocity During DNA Replication - Frontiers
• New model captures the erratic speed of DNA copying proteins in bacteria - EurekAlert!
• Fork coupling directs DNA replication elongation and termination - Science | AAAS
• Plasmid replication initiator interactions with origin 13-mers and polymerase subunits contribute to strand-specific replisome assembly - PNAS
• Viral exploitation of host DNA genome maintenance proteins. - PLOS
• Approaching Protein Barriers: Emerging Mechanisms of Replication Pausing in Eukaryotes - Frontiers
• Protein–DNA complexes are the primary sources of replication fork pausing in Escherichia coli - PNAS
• Study Reveals the Architecture of the Molecular Machine that Copies DNA - Lab Manager
• Researchers exploit rhythm of DNA replication to kill cancer cells - Phys.org
• DNA Replication Revisited: Single-Molecule Analyses Reveal Its Highly Dynamic Nature - Advanced Science News
• Single-Molecule Insights Into the Dynamics of Replicative Helicases - Frontiers
• Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases - PNAS
• Timeless–Tipin interactions with MCM and RPA mediate DNA replication stress response - Frontiers
• Acidic C-terminal tail of the ssDNA-binding protein of bacteriophage T7 and ssDNA compete for the same binding surface - PNAS
• T4 replication: What does “processivity” really mean? - PNAS
• Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective - Frontiers
• Epigenetic Memory Survives DNA Replication with Aid of Histone-Recycling Protein - Genetic Engineering and Biotechnology News
• High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center - Nature
• Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication - Science | AAAS
• DNA damage and Dun1 regulate physical interactions between the helicase MCM and the RNR complex. - PLOS
• Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli - Nature
• Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication - Science | AAAS
• Replication is required for the RecA localization response to DNA damage in Bacillus subtilis - PNAS
• Cost of rNTP/dNTP pool imbalance at the replication fork - PNAS
• Impact of macromolecular crowding on DNA replication - Nature
• Protein collisions derail DNA replication - Laboratory News