Why is "Sex hormone–binding globulin" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-30 16:26:13
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Sex_hormone–binding_globulin entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-30 and was most recently seen on 2026-04-30.
Wikipedia Overview
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens. When produced by the Sertoli cells in the seminiferous tubules of the testis, it is called androgen-binding protein (ABP).
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Trending Topic Today
Search Interest Perspective
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Sex hormone-binding globulin dampens growth and metastasis of breast cancer in an estrogen-independent manner - American Physiological Society Journal
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Circulating SHBG (Sex Hormone-Binding Globulin) and Risk of Ischemic Stroke: - American Heart Association Journals
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Blood lipid levels mediating the effects of sex hormone-binding globulin on coronary heart disease: Mendelian randomization and mediation analysis - Nature
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Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men - The New England Journal of Medicine
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Do Serum Sex Hormone-Binding Globulin, Testosterone Levels Affect CVD Risk in Men? - Endocrinology Advisor
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Pre-binding 18F-FDHT with sex hormone binding globulin permits androgen receptor-specific PET imaging in murine models of prostate cancer - Journal of Nuclear Medicine
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Sex hormone-binding globulin level may predict liver fibrosis for men with NAFLD - Healio
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Association of blood lead with estradiol and sex hormone-binding globulin in 8-19-year-old children and adolescents - Frontiers
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Study: Elevated Sex Hormone-Binding Globulin Protects Against Asthma - HCPLive
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Serum Hormone Concentrations may Help Breast Cancer Risk Management - CancerNetwork
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SEX HORMONE-BINDING GLOBULIN IN NON-CIRRHOTIC ALCOHOLIC PATIENTS DURING EARLY WITHDRAWAL AND AFTER LONGER ABSTINENCE - Oxford Academic
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Effects of weight loss on testosterone, sex hormone-binding globulin, adiposity, and insulin sensitivity in women and men - Wiley Online Library
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Testosterone, sex hormone-binding globulin, insulin-like growth factor-1 and endometrial cancer risk: observational and Mendelian randomization analyses - Nature
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Sex hormone-binding globulin exerts sex-related causal effects on lower extremity varicose veins: evidence from gender-stratified Mendelian randomization - Frontiers
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Tyramine Derivatives as Versatile Pharmacophores With Potent Biological Properties: Sex Hormone–Binding Globulin Inhibition, Colon Cancer Antimigration, and Antimicrobial Activity - Wiley Online Library
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Associations of body composition measures with circulating insulin-like growth factor-I, testosterone, and sex hormone-binding globulin concentrations in 16,000 men | International Journal of Obesity - Nature
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Sex hormone-binding globulin provides a novel entry pathway for estradiol and influences subsequent signaling in lymphocytes via membrane receptor - Nature
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Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis - Nature
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Study shows alcohol-dependent men and women have different biochemistries, so may need different treatments - EurekAlert!
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Specific 18F-FDHT Accumulation in Human Prostate Cancer Xenograft Murine Models Is Facilitated by Prebinding to Sex Hormone–Binding Globulin - Journal of Nuclear Medicine
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Androgen dysfunction in non-alcoholic fatty liver disease: Role of sex hormone binding globulin - Frontiers
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The Free Hormone Hypothesis: When, Why, and How to Measure the Free Hormone Levels to Assess Vitamin D, Thyroid, Sex Hormone, and Cortisol Status - Wiley Online Library
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F-Fluoromethyl-Nortestosterone: Ligands to Determine the Role of Sex Hormone–Binding Globulin for Steroidal Radiopharmaceuticals - Journal of Nuclear Medicine
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Human sex hormone–binding globulin variants associated with hyperandrogenism and ovarian dysfunction - JCI.org
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Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys - Nature
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Diverse Roles for Sex Hormone-Binding Globulin in Reproduction1 - BioOne Complete
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Changes in BMI modulate age-associated changes in sex hormone binding globulin and total testosterone, but not bioavailable testosterone in young adult men: the CARDIA Male Hormone Study - Nature
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Diagnosing and Managing Low Testosterone in CKD - Renal and Urology News
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Androgen Profile in Pre-Menopausal Women With Dry Eye Syndrome - ARVO Journals
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Non-alcoholic fatty liver disease is an influencing factor for the association of SHBG with metabolic syndrome in diabetes patients - Nature
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Testosterone improves lung function in males and females whereas sex hormone-binding globulin has... - Medical Dialogues
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Biochemical Selection of Prepubertal Patients with Androgen Insensitivity Syndrome by Sex Hormone-Binding Globulin Response to the Human Chorionic Gonadotropin Test - Nature
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.