Why is "Stem-loop" trending?

Search Interest Perspective

• -methylguanosine in the U6 internal stem loop facilitates efficient spliceosome assembly - Nature
• Quantitative analysis of small RNA pseudouridylation reveals interplay of PUS enzymes in tRNA anticodon stem-loop - Nature
• Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites - PNAS
• Enhancement of Regnase-1 expression with stem loop–targeting antisense oligonucleotides alleviates inflammatory diseases - Science | AAAS
• A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice - Rockefeller University Press
• Pre-Defined Stem-Loop Structure Library for the Discovery of L-RNA Aptamers that Target RNA G-Quadruplexes - Wiley Online Library
• Stem-Loop IV in the 5′ Untranslated Region Is a cis -Acting Element in Bovine Coronavirus Defective Interfering RNA Replication - ASM Journals
• Stem–loop formation drives RNA folding in mechanical unzipping experiments - PNAS
• Structural basis for 3C and 3CD recruitment by enteroviral genomes during negative-strand RNA synthesis - Nature
• Effects of long DNA folding and small RNA stem–loop in thermophoresis - PNAS
• Structure of HIV-1 RRE stem-loop II identifies two conformational states of the high-affinity Rev binding site - Nature
• A frameshifting stimulatory stem loop destabilizes the hybrid state and impedes ribosomal translocation - PNAS
• Evaluation of Rationally Designed Label-free Stem-loop DNA Probe Opening in the Presence of miR-21 by Circular Dichroism and Fluorescence Techniques - Nature
• Productive mRNA stem loop-mediated transcriptional slippage: Crucial features in common with intrinsic terminators - PNAS
• Identification of antiviral RNAi regulators, ILF3/DHX9, recruit at ZIKV stem loop B to protect against ZIKV induced microcephaly - Nature
• Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation - Nature
• Expanding the mutational spectrum of ReNU syndrome: insights into 5’ Stem-loop variants - Nature
• Structural dynamics of the dengue virus non-structural 5 (NS5) interactions with promoter stem-loop A (SLA) - Nature
• High-throughput DNA melt measurements enable improved models of DNA folding thermodynamics - Nature
• Promotion of TLR7-MyD88-dependent inflammation and autoimmunity in mice through stem-loop changes in Lnc-Atg16l1 - Nature
• RNA stem loop - National Institute of Standards and Technology (.gov)
• Non-canonical RNA substrates of Drosha lack many of the conserved features found in primary microRNA stem-loops - Nature
• SLAM-MS: Mutation scanning of stem-loop amplicons with TaqMan probes by quantitative DNA melting analysis - Nature
• Losing the stem-loop structure from metazoan mitochondrial tRNAs and co-evolution of interacting factors - Frontiers
• Stem loop structure and function - National Institute of Standards and Technology (.gov)
• Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17 - PNAS
• dimer establishes the RNA-binding mechanism of enterovirus protease 3C - Science | AAAS
• Stem-Loop I of the Tembusu Virus 3′-Untranslated Region Is Responsible for Viral Host-Specific Adaptation and the Pathogenicity of the Virus in Mice - ASM Journals
• The TAR Hairpin of Human Immunodeficiency Virus Type 1 Can Be Deleted When Not Required for Tat-Mediated Activation of Transcription - ASM Journals
• Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay - Nature
• RNA stem loop - National Institute of Standards and Technology (.gov)
• The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku - Nature
• Relevance of stem-loop 2 motif in SARS-CoV-2 and astroviruses - News-Medical
• U6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III - Nature
• Few basepairing-independent motifs in the apical half of the avian HBV ε RNA stem-loop determine site-specific initiation of protein-priming - Nature
• NMR Studies of Genomic RNA in 3′ Untranslated Region Unveil Pseudoknot Structure that Initiates Viral RNA Replication in SARS-CoV-2 - ACS Publications
• Terminal hairpins improve protein expression in IRES-initiated mRNA in the absence of a cap and polyadenylated tail - Nature
• Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling - Nature
• Non-Arrhenius kinetics for the loop closure of a DNA hairpin - PNAS
• Ultrasensitive detection of clinical pathogens through a target-amplification-free collateral-cleavage-enhancing CRISPR-CasΦ tool - Nature
• HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry - Nature
• DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells - Nature
• Time-resolved analysis of transcription kinetics in single live mammalian cells - Frontiers
• Secondary structure RNA elements control the cleavage activity of DICER - Nature
• An Efficient LCM-Based Method for Tissue Specific Expression Analysis of Genes and miRNAs - Nature
• U4 small nuclear RNA can function in both the major and minor spliceosomes - PNAS
• Insights into the compact CRISPR–Cas9d system - Nature
• Development of Better Aptamers: Structured Library Approaches, Selection Methods, and Chemical Modifications - Wiley Online Library
• Advancements and applications of loop-mediated isothermal amplification technology: a comprehensive overview - Frontiers
• The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis - ScienceDirect.com
• The 3 31 Nucleotide Minihelix tRNA Evolution Theorem and the Origin of Life - astrobiology.com
• Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase - Nature
• Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex - PNAS
• Secondary structure prediction for RNA sequences including N - Nature
• Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations - Nature
• Iron response elements (IREs)-mRNA of Alzheimer's amyloid precursor protein binding to iron regulatory protein (IRP1): a combined molecular docking and spectroscopic approach - Nature
• Elucidating mechanisms of programmed ribosome frameshifting - Research Projects - Ermolenko Lab - University of Rochester Medicine
• Determinants of effective lentivirus-driven microRNA expression in vivo - Nature
• Revealing the density of encoded functions in a viral RNA - PNAS
• Substrate specificity of human MCPIP1 endoribonuclease - Nature
• Prediction of Immunomodulatory potential of an RNA sequence for designing non-toxic siRNAs and RNA-based vaccine adjuvants - Nature
• In the Loop: Adult stem cells as treatment of the future - Mayo Clinic News Network
• Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution - Nature
• Conserved RNA structures in the intergenic regions of ambisense viruses - Nature
• Selection of highly efficient sgRNAs for CRISPR/Cas9-based plant genome editing - Nature
• Folding of a transcriptionally acting PreQ1 riboswitch - PNAS
• Template switching in DNA replication can create and maintain RNA hairpins - PNAS
• RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand - Nature
• Activation of PKR by a short-hairpin RNA - Scientific Reports - Nature
• Multiplex quantitative analysis of microRNA expression via exponential isothermal amplification and conformation-sensitive DNA separation - Nature
• Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading - Science | AAAS
• In the Loop: Using Stem Cells to Try and Heal Baby Lucas’ Heart - Mayo Clinic News Network
• Small-angle X-ray scattering-derived structure of the HIV-1 5′ UTR reveals 3D tRNA mimicry - PNAS
• First step in pre-miRNAs processing by human Dicer - Nature
• Uses of Short Hairpin RNA (shRNA) Interference - News-Medical
• MS3D structural elucidation of the HIV-1 packaging signal - PNAS
• 5'-Triphosphate-Dependent Activation of PKR by RNAs with Short Stem-Loops - Science | AAAS
• 5′UTR G-quadruplex structure enhances translation in size dependent manner - Nature
• Identification of drought-responsive microRNAs and their targets in Ammopiptanthus mongolicus by using high-throughput sequencing - Nature
• Pseudoknots: RNA Structures with Diverse Functions - PLOS
• Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences - Nature
• Scientists Produce 3-D Image of Retroviral RNA Structure - Lawrence Berkeley National Laboratory (.gov)