Why is "Theophylline" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-04-15 04:57:28
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Theophylline entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-04-15 and was most recently seen on 2026-04-15.
Wikipedia Overview
Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs. Trace amounts of theophylline are naturally present in tea, coffee, chocolate, yerba mate, guarana, and kola nut.
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Trending Topic Today
Search Interest Perspective
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Enzymes related to c-di-GMP turnover in Anabaena and their corresponding mutants. - PLOS
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Real-world use of theophylline in critically ill patients with sinus pauses: a case series - Frontiers
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Prospective Evaluation of Low-Dose Theophylline as an Add-On Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) - Cureus
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Caffeine vs. Theophylline Cocrystals: Insights into Structure–Mechanical Behavior and Piezoelectricity - ACS Publications
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Asthma Drug May Treat Rare Neurological Disorder - respiratory-therapy.com
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Structure, Solubility, and Stability Analysis of Acipimox‐Theophylline Dihydrate Cocrystal - Wiley Online Library
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Cyrano noses toward pivotal trial after midphase smell loss win - Fierce Biotech
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Asthma Drug Reduces Movement Disorder Symptoms - Technology Networks
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Early Cessation of Renal Replacement Therapy in Theophylline Toxicity: A Case Report With Literature Review - Cureus
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A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression - PNAS
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Glenmark orders recall of High BP, COPD drug in US - ET Pharma
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Mixed results for nasal theophylline to treat COVID-related loss of smell - CIDRAP
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Low-Dose Theophylline Not Effective at Reducing COPD Exacerbations, Study Finds - AJMC
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Effect of Theophylline on Sleep-Disordered Breathing in Heart Failure - NEJM
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Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells - Nature
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From Theophylline to Adenine or preQ1: Repurposing a DNA Aptamer Revealed by Crystal Structure Analysis - Wiley Online Library
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Pharmacological treatment for apnoea of prematurity—the need for an individualised approach - Frontiers
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Acute on Chronic Theophylline Toxicity in an Elderly Patient - Cureus
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Theophylline impact on weaning in oxygen-dependent infants followed in an outpatient Kangaroo Program - Frontiers
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Application of a Physiologically Based Pharmacokinetic Model to Study Theophylline Metabolism and Its Interactions With Ciprofloxacin and Caffeine - Navid - 2016 - CPT: Pharmacometrics & Systems Pharmacology - Wiley Online Library - Wiley
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Increased Sensitivity to Theophylline Associated with Primary Open-Angle Glaucoma - ARVO Journals
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Camber Pharmaceuticals Launches Theophylline Extended-Release Tablets - Pharmacy Times
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Theophylline-encapsulated Nile Tilapia fish scale-based collagen nanoparticles effectively target the lungs of male Sprague–Dawley rats - Nature
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Investigations of the Influences of Processing Conditions on the Properties of Spray Dried Chitosan-Tripolyphosphate Particles loaded with Theophylline - Nature
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Does Asthma or Treatment with Theophylline Limit Children's Academic Performance? - NEJM
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A Comparison of Low-Dose Inhaled Budesonide plus Theophylline and High-Dose Inhaled Budesonide for Moderate Asthma - NEJM
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Developmental Changes in Urinary Elimination of Theophylline and Its Metabolites in Pediatric Patients - Nature
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Caffeine Protects Dopaminergic Neurons From Dopamine-Induced Neurodegeneration via Synergistic Adenosine-Dopamine D2-Like Receptor Interactions in Transgenic Caenorhabditis elegans - Frontiers
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Two Distinct Pathways for Metabolism of Theophylline and Caffeine Are Coexpressed in Pseudomonas putida CBB5 - ASM Journals
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Theophylline in Asthma - NEJM
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Effect of Theophylline on Glucose Production and Lipolysis in Preterm Infants (≤32 Weeks) - Nature
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T Wave Inversion Associated with Severe Theophylline Toxicity - ScienceDirect.com
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Modulation of pharmacokinetics of theophylline by antofloxacin, a novel 8-amino-fluoroquinolone, in humans - Nature
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Treatment of the Systemic Capillary Leak Syndrome with Terbutaline and Theophylline: A Case Series - ACP Journals
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A Randomized, Controlled Trial of Theophylline in Patients with Severe Chronic Obstructive Pulmonary Disease - NEJM
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Aminophylline suppresses stress-induced visceral hypersensitivity and defecation in irritable bowel syndrome - Nature
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Effects of Theophylline and Budesonide on Asthma Inflammation Model - Evotec
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Role of Theophylline in Management of Bradycardia Secondary to High Cervical Spinal Cord Injury in a Seven-Year-Old Child: Case Report and a Review of Literature - Cureus
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Effects of Theophylline on Erythropoietin Production in Normal Subjects and in Patients with Erythrocytosis after Renal Transplantation - NEJM
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Pulmonary outcomes following specialized respiratory management for acute cervical spinal cord injury: a retrospective analysis - Nature
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The Value of Maintenance Theophylline in Steroid-Dependent Asthma - NEJM
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Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma - Nature
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Investigation of compressibility and compactibility parameters of roller compacted Theophylline and its binary mixtures - ScienceDirect.com
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Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation - Nature
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The Relation of Product Formulation to Absorption of Oral Theophylline - NEJM
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Effect of Theophylline on Sleep-Disordered Breathing in Heart Failure - NEJM
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Asthma drug theophylline could have possible new use as cough medicine - Imperial College London
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Effects of Theophylline on Diaphragmatic Strength and Fatigue in Patients with Chronic Obstructive Pulmonary Disease - NEJM
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Theophylline Disposition in Patients with Hepatic Cirrhosis - NEJM
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Adding low dose theophylline to inhaled corticosteroids does not reduce COPD exacerbations - NIHR Evidence
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Asthma Not Linked with Premature Birth - respiratory-therapy.com
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Theophylline nasal irrigation studied in COVID-19-related smell loss - Medical Xpress
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Effects of caffeine and theophylline on coronary hyperemia induced by adenosine or dipyridamole - Wiley Online Library
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COVID Olfactory Trial Hints at Possible Benefit - MedPage Today
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Methotrexate and its therapeutic antagonists caffeine and theophylline, target a motogenic T‐cell mechanism driven by thrombospondin‐1 (TSP‐1) - Talme - 2016 - European Journal of Immunology - Wiley Online Library
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One stone two birds: anti-inflammatory bronchodilators as a potential pharmacological strategy for COVID-19 - Frontiers
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New graphite based rapid sensor chip for real-time theophylline monitoring - Phys.org
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The Effects of Bronchodilators on Spontaneous Ventilation and Oxygen Consumption in Rhesus Monkeys - Nature
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Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure - Nature
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Pharmacokinetic Aspects of Theophylline in Premature Newborns - NEJM
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Theophylline for the Treatment of Atrioventricular Block after Myocardial Infarction - ACP Journals
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Adenosine receptor inhibition with theophylline attenuates the skin blood flow response to local heating in humans - Wiley
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Reviving Spermatogenesis: A Case Report on an Approach to Treat Non-obstructive Azoospermia Using Theophylline, Pentoxifylline, and Hyaluronic Acid - Cureus
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Rational Intravenous Doses of Theophylline - NEJM
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Hydrogel-Forming Microneedle Arrays Allow Detection of Drugs and Glucose In Vivo: Potential for Use in Diagnosis and Therapeutic Drug Monitoring - PLOS
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Docs Say No Data to Claim Tea Can Cure COVID-19, It’s a Fake Msg - The Quint
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Electro-catalytic amplified sensor for determination of N-acetylcysteine in the presence of theophylline confirmed by experimental coupled theoretical investigation - Nature
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Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia | Blood Cancer Journal - Nature
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Study reveals a promising method for treating multiple sclerosis - News-Medical
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Doxofylline for Pediatric Asthma Steps 1–4. Pediatric Asthma: New Role for an Old Drug - Frontiers
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Alembic launches Theophylline ER tablets - Drug Store News
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Strides gets USFDA nod for Theophylline extended-release tablets - The Economic Times
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Asthma medication and suicidal ideation: Is there a link? - Medical News Today
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Constructive molecular configurations for surface-defect passivation of perovskite photovoltaics - Phys.org
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Noninvasive respiratory support, methylxanthines among interventions that reduce re-intubations in preterm infants - 2 Minute Medicine
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Glenmark gets USFDA approval for Theophylline ER tablets - ET HealthWorld
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8 Isoniazid Interactions to Watch Out For - GoodRx
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Isolation, analysis and in vitro assessment of CYP3A4 inhibition by methylxanthines extracted from Pu-erh and Bancha tea leaves - Nature
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Damien Hirst | Theophylline FPIA (2003) - Mutual Art
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Zydus Lifesciences gets USFDA nod for asthma drug Theophylline ER - Medical Dialogues
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Rare genetic disease: Researchers discover new treatment for ADCY5-related dyskinesia - Medical Xpress
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Glenmark gets US FDA approval for Theophylline ER Tablets, 300 mg and 450 mg - Express Pharma
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Vietnam detects substandard asthma drug, raising concerns over counterfeit medicines - Tuoi Tre News | The News Gateway to Vietnam
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COVID 19 associated sinus bradycardia effectively treated by Theophylline - Medical Dialogues
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Adenosine Modulates Inspiratory Neurons and the Respiratory Pattern in the Brainstem of Neonatal Rats - Nature
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Strides receive USFDA approval for Theophylline ER tablets, 300 mg and 450 mg - Indian Pharma Post
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Respiratory Cilia as a Therapeutic Target of Phosphodiesterase Inhibitors - Frontiers
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Strides gains USFDA approval for Theophylline Extended-Release Tablets, 300 mg and 450 mg - Express Pharma
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Glenmark Pharmaceuticals receives ANDA approval for Theophylline Extended-release Tablets, 300 mg and 450 mg - ThePrint
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Danger: Don't mix these 8 meds with coffee - MDLinx
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Caffeine Citrate for Apnea of Prematurity: A Prospective, Open-Label, Single-Arm Study in Chinese Neonates - Frontiers
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Caffeine is as effective a remedy for asthmatic children... - upi.com
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She’s purrfect now: Meet the adorable kitty that became the first cat in South Africa to have a partial knee replacement - News24
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Zydus Lifesciences receives final USFDA nod for Theophylline extended-release tablets - Upstox
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The Emergence of the Old Drug Captagon as a New Illicit Drug: A Narrative Review - Cureus
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The Science of Caffeine, The World’s Most Popular Drug - Laughing Squid
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Zydus Lifesciences gets USFDA nod for asthma treatment drug - The Economic Times
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Doctor wins lawsuit over asthma drug - upi.com
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Glenmark Pharma trades flat despite getting USFDA nod for Theophylline ER tablets - Dalal Street Investment Journal
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Historic surgery for cat that fell from second-storey building - The Citizen
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.