Why is "Transcription factor" trending?

Search Interest Perspective

• Transcription factor Etv3 controls the tolerogenic function of dendritic cells - Science | AAAS
• Systematic identification of single transcription factor perturbations that drive cellular and tissue rejuvenation - PNAS
• Electrostatic properties of disordered regions control transcription factor search and pioneer activity - Nature
• Rethinking drug discovery through transcription factor biology - Drug Target Review
• Precisely Defining Transcription Factor Binding Sites - National Institute of Child Health and Human Development (.gov)
• Transcription Factor Drives Chemotherapy Resistance in Ovarian Cancer - Northwestern University
• Transcription factor switching drives subtype-specific pancreatic cancer - Nature
• DNA methylation shapes transcription factor binding beyond canonical CpG contexts - PNAS
• Global maps of transcription factor properties reveal threshold-based formation of DNA-bound and mobile clusters - Science | AAAS
• Multiple overlapping binding sites determine transcription factor occupancy - Nature
• Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq - Nature
• Detecting transcription factor binding sites with PADIT-seq - Nature
• Conformational plasticity of disordered regions enables sequence-diverse DNA recognition by transcription factor AflR - Nature
• GAGA zinc finger transcription factor searches chromatin by 1D–3D facilitated diffusion - Nature
• Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize - Nature
• DNA bendability regulates transcription factor binding to nucleosomes - Nature
• Co-condensation between transcription factor and cBAF selectively modulates chromatin remodeling and gene expression - Nature
• Paused RNA polymerase primes promoters via RNA-mediated stabilisation of transcription factor ERα - Nature
• Epiregulon: Single-cell transcription factor activity inference to predict drug response and drivers of cell states - Nature
• Temporal and context-dependent requirements for the transcription factor Foxp3 expression in regulatory T cells - Nature
• A transcription factor ensemble orchestrates bundle sheath expression in rice - Nature
• Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states - Nature
• Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC - Nature
• Coordinated active repression operates via transcription factor cooperativity and multiple inactive promoter states in a developing organism - Nature
• Transcription factor binding divergence drives transcriptional and phenotypic variation in maize - Nature
• Divergence in a eukaryotic transcription factor’s co-TF dependence involves multiple intrinsically disordered regions - Nature
• The transcription factor GmNAC018 confers salt tolerance in soybean - Frontiers
• Transcription factor T-bet regulates memory B cell subsets - The University of Alabama at Birmingham
• Mechanisms driving functional divergence of transcription factor paralogs - Wiley
• Genome-wide identification of DNA-binding with one finger transcription factor genes in Chinese chestnut and their response to abiotic stress - Frontiers
• Researchers uncover how a key transcription factor reads DNA in human cells - News-Medical
• Low overlap of transcription factor DNA binding and regulatory targets - Nature
• Tuft cells restrain intestinal type 2 immunity through the transcription factor Spi-B - Science | AAAS
• Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer | Cell Death & Disease - Nature
• Heat shock transcription factor-mediated thermal tolerance and cell size plasticity in marine diatoms - Nature
• Genome-wide analysis of RWP-RK transcription factor family reveals its roles in nitrogen response in rice ( Oryza sativa - Frontiers
• DNA-guided transcription factor interactions extend human gene regulatory code - Nature
• Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs - Nature
• dFLASH; dual FLuorescent transcription factor activity sensor for histone integrated live-cell reporting and high-content screening - Nature
• Natural variation in a cortex/epidermis-specific transcription factor bZIP89 determines lateral root development and drought resilience in maize - Science | AAAS
• Transcription factor research illuminates human development pathways - Medical Xpress
• Single-molecule states link transcription factor binding to gene expression - Nature
• Precise modulation of transcription factor levels identifies features underlying dosage sensitivity - Nature
• Nucleosome fibre topology guides transcription factor binding to enhancers - Nature
• Transcription Factor Binding Sites May Help Explain Underlying Causes of Many Diseases - Northwestern University
• Enhancing the interpretability of transcription factor binding site prediction using attention mechanism - Nature
• Multiomic profiling of transcription factor binding and function in human brain - Nature
• Transcription factor networks in cellular quiescence - Nature
• An AP2/ERF transcription factor confers chilling tolerance in rice - Science | AAAS
• Mutations to transcription factor MAX allosterically increase DNA selectivity by altering folding and binding pathways - Nature
• Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance - Nature
• A complete temporal transcription factor series in the fly visual system - Nature
• Histone modifications regulate pioneer transcription factor cooperativity - Nature
• Highly multiplexed design of an allosteric transcription factor to sense new ligands - Nature
• Human transcription factor protein interaction networks - Nature
• Transcription factor binding site orientation and order are major drivers of gene regulatory activity - Nature
• GLABRA2 transcription factor integrates arsenic tolerance with epidermal cell fate determination - Wiley
• Rational optimization of a transcription factor activation domain inhibitor - Nature
• Rice transcription factor bHLH25 confers resistance to multiple diseases by sensing H2O2 | Cell Research - Nature
• Base-resolution models of transcription-factor binding reveal soft motif syntax - Nature
• Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation - Science | AAAS
• Pharmacological restriction of genomic binding sites redirects PU.1 pioneer transcription factor activity - Nature
• Quantification of absolute transcription factor binding affinities in the native chromatin context using BANC-seq - Nature
• Sequence-dependent surface condensation of a pioneer transcription factor on DNA - Nature
• Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA - Nature
• Intrinsically disordered regions as facilitators of the transcription factor target search - Nature
• An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells - Frontiers
• A universal deep-learning model for zinc finger design enables transcription factor reprogramming - Nature
• Inference of age-associated transcription factor regulatory activity changes in single cells - Nature
• Live cell dynamics of the NF-Y transcription factor - Nature
• MYB74 transcription factor guides de novo specification of epidermal cells in the abscission zone of Arabidopsis - Nature
• Transcription factor E4F1 as a regulator of cell life and disease progression - Science | AAAS
• Temporal coordination of the transcription factor response to H - Nature
• Can the Concentration of a Transcription Factor Affect Gene Expression? - Frontiers
• Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation - Nature
• Global reference mapping of human transcription factor footprints - Nature
• Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice - Nature
• Transcription factor clusters as information transfer agents - Science | AAAS
• Generating specificity in genome regulation through transcription factor sensitivity to chromatin - Nature
• Measuring the impact of chromatin context on transcription factor binding affinities - Nature
• Visualizing transcription factor dynamics in living cells | Journal of Cell Biology - Rockefeller University Press
• Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection - Nature
• Researchers uncover the mechanism of action of an important transcription factor - Institute for Research in Biomedicine | IRB Barcelona
• Modeling and designing enhancers by introducing and harnessing transcription factor binding units - Nature
• Mammalian evolution of human cis-regulatory elements and transcription factor binding sites - Science | AAAS
• A redundant transcription factor network steers spatiotemporal Arabidopsis triterpene synthesis - Nature
• Distinct transcription factor networks control neutrophil-driven inflammation - Nature
• Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding - Science | AAAS
• Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions - Nature
• Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content - Nature
• Estimation of Transcription Factor Activity in Knockdown Studies - Nature
• The Sox2 transcription factor binds RNA - Nature
• Lineage specific transcription factor waves reprogram neuroblastoma from self-renewal to differentiation - Nature
• Direct ionic stress sensing and mitigation by the transcription factor NFAT5 - Science | AAAS
• Bone Transcription Factor Controls Nervous System Gene Expression - Northwestern University
• Determinants of transcription factor regulatory range - Nature
• The transcription factor GABPA is a master regulator of naive pluripotency - Nature
• Limited conservation in cross-species comparison of GLK transcription factor binding suggested wide-spread cistrome divergence - Nature
• New Tool Provides Low-Cost, High-Quality Means to Map Transcription Factor Binding Genome-Wide - Research Horizons
• Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions - Nature