Why is "Voltage clamp" trending?
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Trend Analysis
- Ranking position: #
- Date: 2026-03-31 09:46:28
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
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Wikipedia Overview
The voltage clamp is an experimental method used by electrophysiologists to measure the ion currents through the membranes of excitable cells, such as neurons, while holding the membrane voltage at a set level. A basic voltage clamp will iteratively measure the membrane potential, and then change the membrane potential (voltage) to a desired value by adding the necessary current. This "clamps" the cell membrane at a desired constant voltage, allowing the voltage clamp to record what currents are delivered. Because the currents applied to the cell must be equal to the current going across the cell membrane at the set voltage, the recorded currents indicate how the cell reacts to changes in membrane potential. Cell membranes of excitable cells contain many different kinds of ion channels, some of which are voltage-gated. The voltage clamp allows the membrane voltage to be manipulated independently of the ionic currents, allowing the current–voltage relationships of membrane channels to be studied.
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Search Interest Perspective
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High-throughput multiplex voltage-clamp/current-clamp evaluation of acutely isolated neurons - Nature
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What’s the Difference Between a Voltage Clamp and a Current Clamp? - the-scientist.com
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Series resistance errors in whole cell voltage clamp measured directly with dual patch-clamp recordings: not as bad as you think - American Physiological Society Journal
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Voltage-clamp recording from a dentate gyrus granule cell in the presence of glutamate receptor blockers - National Institutes of Health (.gov)
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Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1 - PNAS
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All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals - Nature
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Functional dissection of synaptic circuits: in vivo patch-clamp recording in neuroscience - Frontiers
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Simultaneous NMDA-Dependent Long-Term Potentiation of EPSCs and Long-Term Depression of IPSCs in Cultured Rat Hippocampal Neurons - Journal of Neuroscience
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Protein Makeover with Custom Amino Acids - the-scientist.com
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Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp - Nature
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Multiple mechanisms contribute to fluorometry signals from the voltage-gated proton channel - Nature
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The Hodgkin-Huxley theory of the action potential - Nature
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Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels | Scientific Reports - Nature
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