Why is "X-inactivation" trending?

Search Interest Perspective

• Escape from X inactivation is directly modulated by Xist noncoding RNA - Nature
• X-scape artistry: CTCF insulates X-linked genes from silencing - Fred Hutchinson Cancer Center
• X chromosome-encoded microRNAs in immune regulation: sex differences and clinical implications - Frontiers
• FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single-Cell RNA-Seq Samples - Wiley
• X chromosome switch offers hope for girls with Rett syndrome - University of California - Davis Health
• A tale of two marks: dual modifications on an histone H3.3 govern gene silencing and X-chromosome inactivation - EurekAlert!
• A and the NEXT complex direct Xist RNA turnover and X-inactivation dynamics - Nature
• Human genetic disease - Sex Chromosome Abnormalities - Britannica
• Van Andel Institute scientists develop technique for high-resolution single cell epigenetic analysis - Van Andel Institute
• Loss of chromosome Y shapes the immune cell fate with aging in men - medRxiv
• Imprinted X chromosome inactivation in marsupials: The paternal X arrives at the egg with a silent DNA methylation profile - PNAS
• Retrospective and multifactorial single-cell profiling reveals sequential chromatin reorganization during X inactivation - Nature
• Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype - Nature
• X inactivation shows frail ends when mice age - Nature
• A landscape of X-inactivation during human T cell development - Nature
• A novel quantitative targeted analysis of X-chromosome inactivation (XCI) using nanopore sequencing - Nature
• SPEN integrates transcriptional and epigenetic control of X-inactivation - Nature
• Skewed X-inactivation is common in the general female population - Nature
• Preventing erosion of X-chromosome inactivation in human embryonic stem cells - Nature
• A system to analyze the initiation of random X-chromosome inactivation using time-lapse imaging of single cells - Nature
• Scientists track down mutation that makes orange cats orange - Stanford Medicine
• Defective X-chromosome inactivation and cancer risk in women - Communications Biology - Nature
• GXwasR: A Toolkit for Investigating Sex-Differentiated Genetic Effects on Complex Traits - medRxiv
• Landscape of X chromosome inactivation across human tissues - Nature
• Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling - Science | AAAS
• Population variability in X-chromosome inactivation across 10 mammalian species - Nature
• Targeting Xist with compounds that disrupt RNA structure and X inactivation - Nature
• Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution - Nature
• Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age - Nature
• Gene regulation in time and space during X-chromosome inactivation - Nature
• TLR7 escapes X chromosome inactivation in immune cells - Science | AAAS
• A symmetric toggle switch explains the onset of random X inactivation in different mammals - Nature
• The maternal X chromosome affects cognition and brain ageing in female mice - Nature
• X Chromosome Inactivation Pattern and Pregnancy Outcome of Female Carriers of Pathogenic Heterozygous X-Linked Deletions - Frontiers
• Concurrent X chromosome inactivation and upregulation during non-human primate preimplantation development revealed by single-cell RNA-sequencing - Nature
• Understanding the genetics of X chromosome inactivation - Fred Hutchinson Cancer Center
• Aging activates escape of the silent X chromosome in the female mouse hippocampus - Science | AAAS
• X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients - Nature
• X Inactivation and Escape: Epigenetic and Structural Features - Frontiers
• Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women - Nature
• Xist marks the spot: How an RNA molecule silences the X chromosome - Newsroom | UCLA
• Renal X-inactivation in female individuals with X-linked Alport syndrome primarily determined by age - Frontiers
• SPEN is required for Xist upregulation during initiation of X chromosome inactivation - Nature
• Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation - Nature
• Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias - Nature
• Activation of Xist by an evolutionarily conserved function of KDM5C demethylase - Nature
• ‘Chromosomal Jell-O’ could be key to treating genetic diseases - Harvard Gazette
• Xist -dependent imprinted X inactivation and the early developmental consequences of its failure - Nature
• Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression - Nature
• Skewed X inactivation in Lesch–Nyhan disease carrier females - Nature
• X-chromosome inactivation may reduce autism risk - UW Medicine | Newsroom
• X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body - Frontiers
• Early X chromosome inactivation during human preimplantation development revealed by single-cell RNA-sequencing - Nature
• X Inactivation Is a Good Thing - Science | AAAS
• Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others - PNAS
• Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: The Lyon repeat hypothesis - PNAS
• X-chromosome inactivation: counting, choice and initiation - Nature
• Novel players in X inactivation: insights into Xist -mediated gene silencing and chromosome conformation - Nature
• X inactivation in triploidy and trisomy: the search for autosomal transfactors that choose the active X - Nature
• Unfavorable switching of skewed X chromosome inactivation leads to Menkes disease in a female infant - Nature
• Spatial partitioning of the regulatory landscape of the X-inactivation centre - Nature
• הפעילות הסודית של הכרומוזום השקט - מכון דוידסון לחינוך מדעי
• A first-generation X-inactivation profile of the human X chromosome - PNAS
• X Chromosome inactivation: a modifier of factor VIII and IX plasma levels and bleeding phenotype in Haemophilia carriers - Nature
• BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation - Nature
• X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils - PNAS
• Roles of the Rlim–Rex1 axis during X chromosome inactivation in mice - PNAS
• X-inactivation profile reveals extensive variability in X-linked gene expression in females - Nature
• Case Report: De novo DDX3X mutation caused intellectual disability in a female with skewed X-chromosome inactivation on the mutant allele - Frontiers
• Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation - Nature
• Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice - PNAS
• X-chromosome inactivation altered in SLE - Nature
• Nuclear positioning and pairing of X-chromosome inactivation centers are not primary determinants during initiation of random X-inactivation - Nature
• Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation - Nature
• X inactivation by titration - Nature
• An Xist-activating antisense RNA required for X-chromosome inactivation - Nature
• Researchers Identify Genetic Mutation Responsible for Orange Coat in Domestic Cats - Sci.News
• X Chromosome Inactivation Timing is Not eXACT: Implications for Autism Spectrum Disorders - Frontiers
• The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist - Nature
• Sex Chromosome Inactivation: The Importance of Pairing - ScienceDirect.com
• Rlim/Rnf12, Rex1, and X Chromosome Inactivation - Frontiers
• Reprogramming X Inactivation - Science | AAAS
• Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control - Nature
• Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations - PNAS
• X Inactivation: Pre- or Post-Fertilisation Turn-off? - ScienceDirect.com
• Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation - Nature
• An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells - PNAS
• The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice - Nature
• Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation - Nature
• Female mice lacking Ftx lncRNA exhibit impaired X-chromosome inactivation and a microphthalmia-like phenotype - Nature
• Diverse factors are involved in maintaining X chromosome inactivation - PNAS
• Exploring Autoimmune Prevalence and X Chromosome Inactivation in Systemic Lupus Erythematosus - Lupus Foundation of America
• Phase separation drives X-chromosome inactivation - Nature
• X Chromosome Inactivation Surprisingly Found in Diverse Cancers in Men - Genetic Engineering and Biotechnology News
• Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape - Nature
• X-inactivation in the clinical phenotype of fragile X premutation carrier sisters - Neurology® Journals
• X-Chromosome Inactivation and Autosomal Random Monoallelic Expression as “Faux Amis” - Frontiers
• DNA Methylation and X-Chromosome Inactivation in Placenta - Bioengineer.org
• Stanford Medicine-led study shows why women are at greater risk of autoimmune disease - Stanford Medicine
• Direct Detection of Non-Random X Chromosome Inactivation by Use of a Transcribed Polymorphism in the XIST Gene - Nature