Why is "Xeroderma pigmentosum" trending?
Latest news, Wikipedia summary, and trend analysis.
Trend Analysis
- Ranking position: #
- Date: 2026-05-13 21:15:21
This topic has appeared in the trending rankings 1 time(s) in the past year. While it does not trend frequently, its appearance suggests a renewed or concentrated surge of public interest.
Based on Wikipedia pageviews and search interest, this topic gained significant attention on the selected date.
Trend Insight
Xeroderma_pigmentosum entered the ranking for the first time today at position #. This is its highest position ever recorded.
Trend History
This topic has appeared in the English Wikipedia rankings 1 time. It first appeared on 2026-05-13 and was most recently seen on 2026-05-13.
Wikipedia Overview
Xeroderma pigmentosum (XP) is a genetic disorder in which there is a decreased ability to repair DNA damage such as that caused by ultraviolet (UV) light. Symptoms may include a severe sunburn after only a few minutes in the sun, freckling in sun-exposed areas, dry skin and changes in skin pigmentation. Nervous system problems, such as hearing loss, poor coordination, loss of intellectual function and seizures, may also occur. Complications include a high risk of skin cancer, with about half having skin cancer by age 10 without preventative efforts, and cataracts. There may be a higher risk of other cancers such as brain cancers.
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Trending Topic Today
Search Interest Perspective
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Type I interferon signaling defines a novel disease signature in xeroderma pigmentosum C human keratinocytes - Nature
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Clinical Spectrum of Xeroderma Pigmentosum: An Observational Study - Cureus
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JEADV Clinical Practice | Clinical Dermatology and Venereology Journal - Wiley Online Library
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Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model - Nature
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Campers Live It Up at Night by Necessity - ABC News - Breaking News, Latest News and Videos
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What is xeroderma pigmentosum? 'I'm allergic to the sun' - thatslife.com.au
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The Price of Exposure: Xeroderma Pigmentosum and Skin Cancer - Cureus
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Translocation mechanism of xeroderma pigmentosum group D protein on single-stranded DNA and genetic disease etiology - Nature
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Sunlight Sensitivity Disorder Tied to Squamous Cell Carcinoma - EMJ
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Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C - PNAS
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Influencing and Improving Photoprotection Behaviors in Patients With Xeroderma Pigmentosum - Dermatology Times
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Metastatic Squamous Cell Carcinoma Treated With Pembrolizumab in a Patient With Xeroderma Pigmentosum - Wiley Online Library
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Juvenile Granulosa Cell Tumor in an Adolescent With Xeroderma Pigmentosum: A Rare Case and Implications for Surveillance - Cureus
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Immune checkpoint inhibitors for children with xeroderma pigmentosum and advanced cutaneous squamous cell carcinoma: A case presentation and brief review - Wiley Online Library
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Synthetic rescue of Xeroderma Pigmentosum C phenotype via PIK3C3 downregulation | Cell Death & Disease - Nature
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Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients - Nature
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Inflammatory landscape in Xeroderma pigmentosum patients with cutaneous melanoma - Nature
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Early-onset gynecological tumors in DNA repair-deficient xeroderma pigmentosum group C patients: a case series - Nature
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Xeroderma pigmentosum protein XPD controls caspase-mediated stress responses - Nature
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Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant - Nature
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Case report: Xeroderma pigmentosum Group A with erythropoietic protoporphyria in a young Chinese patient - Frontiers
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Unresectable and chemoresistant conjunctival squamous cell carcinoma on xeroderma pigmentosum treated by salvage radiation therapy: A case report and a review of the literature - Wiley Online Library
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Whole-Exome Sequencing Enables the Diagnosis of Variant-Type Xeroderma Pigmentosum - Frontiers
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Founder Mutations in Xeroderma Pigmentosum - ScienceDirect.com
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An adolescent case of xeroderma pigmentosum variant confirmed by the onset of sun exposure-related skin cancer during Crohn's disease treatment - Wiley Online Library
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p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene - PNAS
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Xeroderma Pigmentosum with Simultaneous Cutaneous and Ocular Squamous Cell Carcinoma - Dove Medical Press
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Xeroderma Pigmentosum With Ocular Surface Squamous Neoplasia: A Case Report - Cureus
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Cigarette smoke and DNA repair deficiency drive lung cancer development - EurekAlert!
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Molecular analysis of mutations in DNA polymerase η in xeroderma pigmentosum-variant patients - PNAS
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New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair - EurekAlert!
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The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts - PNAS
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UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, γ-H2AX formation, and Mre11 relocalization - PNAS
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Malignant Rhabdoid Tumor of the Kidney in a Child With Xeroderma Pigmentosum: Incidence or Coincidence? - Cureus
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Clinuvel reports data from xeroderma pigmentosum therapy trial - Clinical Trials Arena
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New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair - Phys.org
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SUMOylation of xeroderma pigmentosum group C protein regulates DNA damage recognition during nucleotide excision repair - Nature
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Verrucous Carcinoma of Tongue in Xeroderma Pigmentosum: A Case Report and Literature Review - Cureus
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Xeroderma pigmentosum linked to high incidence of eyelid and ocular surface malignancies - American Academy of Ophthalmology
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Novel pathogenic frameshift mutation in the POLH gene contributes to xeroderma pigmentosum variant type in a 16-year-old girl - Wiley Online Library
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Xeroderma Pigmentosum Group G with Severe Neurological Involvement and Features of Cockayne Syndrome in Infancy - Nature
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What If a Day in the Sun Could Kill You? - Men's Health
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Children of the Night - The Atlantic
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Calls to assess neurological symptoms of rare genetic disorder | UCL News - UCL - UCL | University College London
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Xeroderma Pigmentosum: A Multidisciplinary Approach - EMJ
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Cancer in xeroderma pigmentosum and related disorders of DNA repair - Nature
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Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases - Nature
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Multiple facial basal cell carcinomas in xeroderma pigmentosum treated with topical imiquimod 5% cream - Wiley Online Library
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Abnormal XPD -induced nuclear receptor transactivation in DNA repair disorders: trichothiodystrophy and xeroderma pigmentosum - Nature
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NSW sisters with rare condition need help to build UV-safe backyard sanctuary before Christmas - 7NEWS
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Case report: Neoadjuvant-intent pembrolizumab resulted in complete response in a xeroderma pigmentosum patient with locally advanced resectable cutaneous squamous cell carcinoma of the nose - Frontiers
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Trolls Called Her ‘Irresponsible’ For Having Baby, Now The Internet Is Saving Her Life - AOL.com
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What You Need to Know About the Rare Genetic Disease in Bella Thorne's New Movie - Teen Vogue
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Orange County teen with rare disease is crowned homecoming queen - ABC7 Los Angeles
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Long-term outcome of bilateral penetrating keratoplasty in a child with xeroderma pigmentosum: case report and literature review - Nature
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Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas - PNAS
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Genetics students gain rare opportunity to learn about living with rare disease - Roanoke College
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Late Presentation of Xeroderma Pigmentosa With Squamous Cell Carcinoma in Septic Shock: Report of a Rare Case - Cureus
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Limbal stem cell deficiency and xeroderma pigmentosum: a case report - Nature
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A Brazilian Village Where Residents Are Literally Melting Away - Fox News
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XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature - Nature
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PROFILE: Riley McCoy lives with Xeroderma Pigmentosum. - Orange County Register
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Xeroderma Pigmentosum: Parents helpless, doctors baffled as authorities remain blind to child-killing 'chukki kayle' - The South First
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Quick to Sunburn? Extreme Sun Sensitivity a Sign of Two Rare Genetic Conditions - UVA Health
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Xeroderma Pigmentosum: Ball now in government's court, but it has miles to go to save children from premature death - The South First
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Meet the two Aussie sisters who can only play outside after dark. - Mamamia
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Rare genetic disease ravages village in Brazil (graphic images) - CBS News
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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η - Nature
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TACG - Dove Medical Press
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Prevention of Skin Cancer in Xeroderma Pigmentosum with the Use of Oral Isotretinoin - The New England Journal of Medicine
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Roanoke mother hosts Moonlight Ball to help children with rare disorder - WDBJ7
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For Kids With 'XP' Skin Condition, Sun Is Worst Enemy - NBC News
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Boy lives in permanent shade to survive dangerous sunlight - Reuters
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The clinical spectrum associated with ERCC5 mutations: Is there a relationship between phenotype and genotype? - Wiley Online Library
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New findings shed light on the repair of UV-induced DNA damage - EurekAlert!
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Children of the Night - Reuters
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New film spotlights genetic disease among Navajos - Deseret News
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What is XP - or xeroderma pigmentosum? - BBC
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'Miracle' Ontario siblings battle XP, rare disease causes extreme sunlight sensitivity - CBC
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7-Year-Old California Boy Lives with Incurable Rare Condition that Makes Sunlight Deadly - People.com
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Olivia Holden: Night garden for XP girl 'allergic to sun' - BBC
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Sunlight Hurts People With Rare Condition - VOA - Voice of America English News
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Research News: The Structure of XPD Sheds Light on Cancer and Aging - Lawrence Berkeley National Laboratory (.gov)
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Moroccans struggle with skin disorder - Arab News
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Xeroderma pigmentosa with ocular association: Case report - SCIRP Open Access
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Woman’s rare illness xeroderma pigmentosum means UV light causes severe burns, blisters, cancer - WCVB
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Inventing headwear for people with UV allergy sensitivity - King's College London
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A life in the shadows: India's XP children, in pictures - The Telegraph
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Rare, genetic skin-eating disease "XP" afflicts Brazil village - CBS News
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Miss Legacy Zim fights xeroderma pigmentosum condition - The Herald ZW
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South First Impact: Karnataka health minister visits children battling Xeroderma Pigmentosum - The South First
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Xeroderma pigmentosum in black South Africans - Jacyk - 1999 - International Journal of Dermatology - Wiley Online Library
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Rare Skin Disease Makes People In Brazilian Village 'Melt Away': What Is Xeroderma Pigmentosum? - Medical Daily
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Rare disease afflicts Brazilian village - Medical Xpress
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Rare disease afflicts Brazilian village - Worcester Telegram
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South First Impact: Govt continues effort to address Xeroderma Pigmentosum in Chamarajanagar's children, prepares action report - The South First
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Good news for children of the Moon 🌙 - Techno-Science.net
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Slideshow: Gruesome disease allows sun to melt people's skin - Arizona Daily Star
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What's Bella Thorne's Condition In The Movie Midnight Sun? - Refinery29
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When daylight kills: India's XP children - The Telegraph
Why This Topic Is Trending
This topic has recently gained attention due to increased public interest. Search activity and Wikipedia pageviews suggest growing global engagement.
Search Interest & Related Topics
Search interest data over the past 12 months indicates that this topic periodically attracts global attention. Sudden spikes often correlate with major news events, public statements, or geopolitical developments.